Mucolipidosis type X is a lysosomal storage disease that was suggested to be a result of impaired mannose 6-phosphate receptor function. How would you test that
Q: Identify any factors or special needs which may affect the test or test results including the need…
A: The majority of laboratory tests prescribed globally are blood tests. Factors affecting test…
Q: VNTR markers: 0 ☐ 0 are usually detected by DNA sequencing are the first used by forensic services…
A: VNTRs (Variable number tandem repeats) also referred to as microsatellites or simple sequence length…
Q: Sometimes, genetic make-ups do not show up as traits. Let us assume Jane has beautiful brown eyes.…
A: Given: Phenotype of Jane's father - blue eyes. Since her father has pure bred blue eyes, he is…
Q: From the following DNA strand: AAGCTAGGATTGCC How many codons would be present?
A: A codon is made up of three nucleotides. Such codons are abundant in messenger RNA and consist of a…
Q: 5. Carbohydrate metabolism involves glycolysis, the Krebs cycle, and the electron transport chain.…
A: Carbohydrates are macronutrient which are present in food and act as main source of energy There…
Q: Mosquitoes and ticks transmit pathogens to mammals. For each vector, explain how the life cycle,…
A: The illnesses brought on by vectors are known as vector borne diseases. A vector, such as a…
Q: I am more so wondering about the structural differences between the two cells, like the organelle…
A: Lymphocytes plays an important role in determining the immunity of an individual. It can be divided…
Q: A technician wants to amplify DNA from a patient sample. However, the lab is not equipped with a…
A: DNA amplification is a technique used to make multiple copies of a specific DNA sequence. It is…
Q: List all steps involved in a cloning workflow. Name and link the appropriate enzymes to the steps at…
A: Gene cloning involves the following basic 7 steps: Obtaining DNA fragments from the target gene…
Q: III OIV VII OVI Figure 1: Family pedigree tracing a genetic disease.
A: Inheritance pattern is a type of pattern which determines how traits are passed on from parental…
Q: our short answer should be 2-5 sentences depending on the question. (Ch. 50). Please answer both…
A: The several kinds of sensations that humans are capable of perceiving are used to guide our motor…
Q: Background: There are ten major phyla that represent the invertebrate animals. Though they all share…
A: The answer is not based on the lesson you have mentioned but the answer is from general knowledge.…
Q: 1. DNA- CGTACGTCAGCG RNA-? Amino acid? 2. DNA- GACAGTCAGATT RNA? Amino acid? 3. DNA? RNA-…
A: 1. DNA : CGTACGTCAGCG RNA : GCAUGCAGUCGC Amino acid : Ala-Cys-Ser-Arg 2. DNA : GACAGTCAGATT RNA :…
Q: What difference between these two variants makes the transmission of Borrellia burgdorferi lower in…
A: Ixodes scapularis is sometimes referred to as the bear tick in some regions of the US, and the deer…
Q: Briefly explain the two processes of transcription and translation and highlight the roles of the…
A: Transcription is a process in which RNA is synthesised with the help of template strand of DNA.…
Q: How many Illumina clusters would you need to generate 15X coverage of the human genome, assuming…
A: Formula: C=LNG C stands for coverage G is the haploid genome length L is the read length N is the…
Q: The team would now like to establish the smallest possible deletion that would inactivate the…
A: Amino acid monomers form the building blocks of proteins. The arrangement of amino acids makes up a…
Q: Dunkers are part of a religious group which originated from 27 families that emigrated from Germany…
A: As we can see, there is a significant difference in the frequency of alleles between the two…
Q: Predict what might happen if plants were able to absorb more carbon dioxide. How will this affect…
A: The current level of carbon dioxide concentration in atmosphere (0.03%) is suboptimal for the C3…
Q: Give 4 similarities and 4 differences between the condensation of DNA during mitosis and the folding…
A: Condensation of DNA is the process by which a double-stranded molecule of deoxyribonucleic acid…
Q: What are some benefits that come with sexual reproduction? Please select all correct answers. a.…
A: Reproduction is a biological process possessed by living organisms to promote their number in nature…
Q: Discuss how the use of antimicrobial agents selects for resistant microbes and explain how…
A: Antibiotic and antifungal use puts pressure on bacteria and fungi to adapt, which speeds up the…
Q: Eukaryote cells are living cells that are specialized to deal with changes in the external…
A: Introduction: When a cell wants to engulf something, it binds to it on the cell surface and draws it…
Q: Draw/attach a picture showing sugar fermentation of yeast involving the enzyme and explain. Relate…
A: 1. Fermnetation of yeast involves glycolysis as its first step. After glycolysis, enzymes pyruvate…
Q: can SDS-PAGE be used to determine the mass of a multimeric protein?
A: SDS-PAGE (sodium dodecyl sulphate-polyacrylamide gel electrophoresis) is a widely used technique in…
Q: WHEN do you think apoptosis occurs in humans? - What would be the effect if apoptosis doesn't…
A: ANSWER) Apoptosis is described as the natural programmed cell death occuring in the multicellular…
Q: When you cross a female carrier for Color Blindness XCXc with a Color Blind male XcY, what is the…
A: An imbalance in how one or more light-sensitive cells (known as cones) located in the retina of the…
Q: lipase an enzyme?
A: Enzyme is usually a protein molecule that acts on a reaction and increases the speed of the reaction…
Q: DO NOT COPY IN GOOGLE OR BARTLEBY QUESTION: Why is there a need for replica plating? How is…
A: Replica plating is technique related to microbiology. In replica plating colonies inoculated into…
Q: Explain what a competitive antagonist is using a named example. In your answer, explain why a…
A: Antagonist is a chemical substance like a drug which may block the action of the agonist after…
Q: A patient is diagnosed with lung cancer using imaging. To establish the best treatment option,…
A: Since you've asked multiple questions, we're only answering the first three for you. If you want any…
Q: why the therapeutic effect takes weeks to manifest while side-effects occur immediately in tricylic…
A: Depression and anxiety are significant disorders that frequently need medical treatment. Anxiety is…
Q: what is the frequency of the rarest variant you can detect during deep sequencing of a tumor cell if…
A: A tumour cell is a type of abnormal cell that is produced and reproduces at an abnormally rapid…
Q: Maple syrup urine disease may be due to an autosomal recessive mutation. Data indicate that the…
A: Given that, Maple syrup urine disease is autosomal recessive. The prevalence of this disease is…
Q: Human genes were integrated into the chromosomes of pig sperm using the procedure of sperm-mediated…
A: Q.1Ans:- B. DNA Replication. Explanation:- if we integrate the human sperm into the pig sperm…
Q: How do you differentiate a nodule from a root gall?
A: Abnormal outgrowths of plant tissues and can be caused by nematodes is gall and nodule is formad by…
Q: Determining age at death for sub-adults is achieved by looking at the degree of epiphyseal fusion in…
A: Fusion of different bones occurs at age (years): Humerus distal end : 13-16 Femur proximal end :…
Q: What is NOT true about the function of RNA polymerase? O its rate of activity is similar for all the…
A: Promoter sites are short DNA sequences found in the promoter region of a gene. They act as binding…
Q: How has the significance of science knowledge changed over the centuries from the point of view of…
A: Scientific knowledge is crucial to our understanding of the world around us and how it works. It…
Q: Which of the following hypothetical islands would likely have the greatest species richness?
A: Biodiversity, often known as biological diversity, refers to the variety of life that can be found…
Q: Predict what might happen if microorganisms began releasing methane. How will this affect the…
A: A greenhouse gas is a gas that ingests and radiates energy inside the thermal infrared range,…
Q: Use the following information to answer the next question. Life Cycle of a Butterfly Adult…
A: Nondisjunction in meiosis II comes from the failure of the sister chromatids to split during…
Q: Summarize the following in concise and understandable language.
A: SARS-CoV-2 It is Severe acute respiratory syndrome coronavirus 2 which is a strain of coronavirus…
Q: What are "genetic biohackers" in reference to "do it yourself CRISPR kits"?
A: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a gene-editing technology that…
Q: Some Traits in Garden Pea Plants In pea plants, the genes for seed shape, seed colour, and plant…
A: The method GREGOR MENDEL described as a cross to identify the hidden characters is known as a…
Q: 5 Multiple Choice Provided below is a dichotomous key for determining the kingdom of an organism. 1a…
A: Answer : a unicellular organism that lives in pond and lacks nucleus would be classified as a member…
Q: Define what the “Theory of Mind” means and explain its importance to primate social behavior.
A: Social behaviour is a kind of behaviour in which various members of the group help each other to…
Q: The response. B cells, humoral O T cells, humoral produce antibodies as part of the O macrophages,…
A: Introduction: Immune system component known as an antibody that circulates in the blood and lymph in…
Q: How does adaptation of the hair cell response occur when the same frequency is sensed? Myosin holds…
A: Myosin is a type of motor protein that is found in muscle tissue. It is responsible for muscle…
Q: Taste cells form chemical synapses with afferent neurites that make up the gustatory cranial nerve.…
A: Introduction A neuron will secrete a neurotransmitter to communicate with another cell across a…
Mucolipidosis type X is a lysosomal storage disease that was suggested to be a result of impaired mannose 6-phosphate receptor function. How would you test that? I need an example of a quantitative assay.
Step by step
Solved in 2 steps
- How does the loss of the Adenomatous polyposis coli (APC) protein lead to the deregulation of Beta-catenin functions in FAP patients?One of the early results shows that the post-centrifugation pellet of encapsulated cells also contains EA1 and/or Sap. Why is this not proof that Bacillus anthracis cells have both an S-layer and a capsule simultaneously? I need help finding the answer in the article and explain in short answer link to article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106848/Which letter represents the target site of furosemide (Lasix)? E- -B
- In addition to the many pharmaceutical products available to treat various diseases, there are also many “natural remedies” that may treat the same diseases, though they do not have FDA approval. For example, Dramamine was developed to treat nausea, but many tout ginger as an effective remedy for nausea. Despite the potential of these natural remedies, pharmaceutical companies do not invest in the development of these natural remedies to obtain FDA approval. Explain why this is the case, and what might be a potential solution to this underinvestment.Resistance to many penicillins is the result of cell wall mutations in a variety of bacteria. True or false?Briefly describe the effects of colchicine treatment on cells. What are the genetic implications of such effects?
- A patient has a blood bank history of being type A positive. The patient has recently been diagnosed with carcinoma of the colon and now the reagent anti-B is showing a 1+ reaction with the patient's cells. Other typing results are as expected. Please explain.Some people have a genetic predisposition for developing priondiseases. Examples are described in Table 25.6. In the case ofGerstmann-Straüssler-Scheinker disease, the age of onset istypically 30–50 years, and the duration of the disease (whichleads to death) is about 5 years. Suggest a possible explanationwhy someone can live for a relatively long time withoutsymptoms and then succumb to the disease in a relativelyshort time.Kelly has breast cancer. Her doctors determined her breast cancer wasaggressive, which meant that she needed to undergo chemotherapy. Her doctors recommended a combination of docetaxel (Taxotere®), carboplatin, and trastuzumab (Herceptin®). The following is her blog entry after her second chemo treatment: As far as chemo symptoms go, the biggest has been fatigue. I was just tired, grumpy, and not my usual, peppy self most of the week. Other very minor things—tiny bit of stomach upset at the beginning of the week, but just enough to make me not feel like eating a big steak, not enough to keep me from eating soup or sandwiches. My scalp felt a little irritated—for the girls out there, itwas the feeling of having my hair in a tight ponytail all day and then letting it down, and the follicles just feel prickly—this is normal for several daysbefore the hair falls out. Also, I have a weird dry mouth feeling, so some things taste a little different. But seriously, these are really minor…
- Under cellular conditions, dATP can be oxidized to its 2-hydroxy form, which is a substrate for an enzyme that converts 2-OH-dATP to 2-OH-dAMP + PPi. Explain why compounds that inhibit the activity of this enzyme would be eff ective anticancer agents.Why is there caution against prescribing imatinib with strong CYP3A4 inhibitors?What is the attached enzyme in this assay and its corresponding substrate? A. Horseradish peroxidase and OPD (o-phenylenediamine dihydrochloride) B. Horseradish peroxidase and PNPP (p-Nitrophenyl Phosphate, Disodium Salt) C. Horseradish peroxidase and TMB (3,3',5,5'-tetramethylbenzidine) D. Horseradish peroxidase and ABTS (2,2'-azinobis-3-ethylbenzothiazoleine-6- sulfonic acid)