Meclizine is an antiemetic (it helps prevent or at least lessen the throwing up associated with motion sickness, including seasickness). Among the names of its over-the-counter preparations are Bonine, Sea-Legs, Antivert, and Navicalm. వియి-సిగాం H,N Cl 3-Aminomethyl- toluene Meclizine „00- `NH2 ČOOH CI CI Chloro- Benzoic Ethylene benzene acid oxide Do

Chemistry: Principles and Reactions
8th Edition
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:William L. Masterton, Cecile N. Hurley
Chapter22: Organic Chemistry
Section: Chapter Questions
Problem 28QAP: When the conjugate acid of aniline, C6H5NH3+, reacts with the acetate ion, the following reaction...
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Given this retrosynthetic analysis, show how meclizine can be synthesized from the four named organic starting materials.

Meclizine is an antiemetic (it helps prevent or at least lessen the throwing up associated
with motion sickness, including seasickness). Among the names of its over-the-counter
preparations are Bonine, Sea-Legs, Antivert, and Navicalm.
వియి-సిగాం
H,N
Cl
3-Aminomethyl-
toluene
Meclizine
„00-
`NH2
ČOOH
CI
CI
Chloro-
Benzoic
Ethylene
benzene
acid
oxide
Do
Transcribed Image Text:Meclizine is an antiemetic (it helps prevent or at least lessen the throwing up associated with motion sickness, including seasickness). Among the names of its over-the-counter preparations are Bonine, Sea-Legs, Antivert, and Navicalm. వియి-సిగాం H,N Cl 3-Aminomethyl- toluene Meclizine „00- `NH2 ČOOH CI CI Chloro- Benzoic Ethylene benzene acid oxide Do
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