Match the following 1) ____Point mutation, 2)____Nonsense mutation, and 3) ____Silent mutation     A. Mutations that result in an inappropriate stop codon and a polypeptide of improper length. B. These mutations alter the DNA sequence of nucleotides but does not result in any alteration to the polypeptide produced.            C. This type of alteration of nucleic acid structure could be the result of an error in the proofreading performed by DNA polymerase. D. This type of polypeptide mutation results in one amino acid being altered but the length of the chain being the same.

a. Some antibiotics, such as rifampin, interfere with the function of RNA polymerase. What biological process is rifampin disrupting?     b. Some antibiotic-resistant M. tuberculosis bacteria have a single point mutation (CàT) in the rpoB gene that causes an amino acid change from serine (a polar amino acid) to leucine (a non-polar amino acid). What type of mutation is this? Do you expect this to have no effect, a small effect, or a large effect on the polypeptide produced? Explain your reasoning.         c. The rpoB gene encodes a subunit of the bacterial RNA polymerase protein. The point mutation described in Question 2 causes a change in protein folding, which leads to the inability of the rifampin antibiotic to bind to the RNA polymerase. Which level(s) of protein structure is/are affected by this change?

An individual with the genetic condition cystic fibrosis has CFTR protein with the amino acid histidine (at position 482), where the normal CFTR protein has arginine. No other changes are observed in the protein. This is the result of a ____ mutation. Select one: a. nonsense b. frameshift c. silent d. missense

I mutation occurs such that the sequence now reads: CTA CTT TTT. A) Transcribe the short DNA sequence. B) translate this short DNA sequence. C) what type of point mutation is this? A mutation occurs such that the sequence now reads: CTA GTC TTT. 1)transcribe this short DNA sequence. 2. Translate this short DNA sequence. 3. What type of point mutation is this?

If the codon AAA is mutated to AAG, it still codes for the amino acid, lysine, and the protein remains functionally the same; which of the following would best describe the result of this mutation? 1) frameshift mutation. O 2) insertion mutation. O 3) silent mutation. 4) nonsense mutation. O 5) back mutation.

Faulty DNA repair; ii) Gain-of-function; and iii) Trinucleotide repeats  provide genetics disorders Give examples of mutations with each disorder.

Identify which mutation is most likely to impact the function of the protein it encodes a) silent mutation  b) mutation at the third site of a codon c) nonsense mutation d) missense mutation

All questions  a) State the type of gene mutation shown in Figure 2.  b) Name the genetic disorder that would arise from this mutation.  c) What is the difference(s) between gene mutation shown in Figure 2 from a frameshift mutation?

The following sequence represents a few codons present in one strand of DNA.Using this strand of DNA as a template strand for transcription, you are required to synthesize a new RNA strand.  A) Show the codons that will be present on the RNA strand.  B) Using the universal genetic code, provide the amino acids on the protein that will be translated from the RNA strand.  3’ TAC ATG GTT GTG CTA ATT 5’

1. (a) Which of the following statements is TRUE?     DNA polymerase moves in a 5 to 3 direction in proofreading and correcting synthesized DNA.     RNA polymerase moves in a 5 to 3 direction in synthesizing mRNA.     Ribosome moves in a 3 to 5 direction during translation.     tRNA moves in a 3 to 5 direction during translation. (b) "In this mutation, most amino acids are replaced due to a deletion of a nucleotide base."     missense mutation     nonsense mutation     silent mutation     frameshift mutation