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- CD8 cells attack virally infected cells, usually killing them using what method? 1) Complement activation O2) 2) Apoptosis O 3) Phagocytosis O 4) Senescence33) During maturation, B cells expand their endoplasmic reticulum. What is the function of this? A) The endoplasmic reticulum is needed to promote genetic recombination during maturation B) An enlarged endoplasmic reticulum is needed to accommodate enhanced secretion of antibodies C) The extra membrane is needed for phagocytosis of pathogens D) The endoplasmic reticulum contributes to epithelial mesenchymal transition of B cells during maturation E) B cells secrete large amounts of extracellular matrix proteins to promote wound repairThe figure above depicts an antibody. For the labeled areas, which statement among A-D is not correct? A) O Mature, functional IgA antibodies possess a total of two sites labeled A B) O Your IgM antibodies are all similar in these areas: A C) O During opsonization, area B would bind to a bacterium D) O Your IgD antibodies are all different in this area: B 111 E) O None are matched correctly. B.
- Explain the mechanism underlying the molecular structure of C7, C8, and C9 complement protein that facilitates their insertion into the cell membrane of a pathogen?Describe the two methods a bacterial cell dies due to activating the complement system;Complement proteins function in defense by _______. a. neutralizing toxins b. enhancing resident bacteria c. promoting inflammation d. forming pores that cause pathogens to disintegrate e. both a and b f. both c and d
- 42. Answer (a) for TRUE or (b) for C3a and C5b are anaphylatoxins. 43. Answer (a) for TRUE or (b) for FALSE to the following statement: on C3 and C5 convertases are generated from all complement pathways. 44. Answer (a) for TRUE or (b) for FALSE to the following statement: While the Clq protein starts the classical pathway, the complement MBL protein starts the pathway. 45. Answer (a) for TRUE or (b) for FALSE to the following statement MHC-II can present to CD8+ T cells and can be loaded with 13 amino acids 46. Regarding the figure below, choose (a) for tissue rejection or (b) for NO tissue rejection: Recipient haplotype Donor haplotype Host B Host AxB C 244Removal of apoptotic cells are done by: Question 6 options: a) phagocytes or neighboring cells. b) circulatory system sweeping away the fragmented cells. c) fragmentation of the cell into small enough pieces that they are swept away by extracellular fluid. d) fusion of the apoptotic cell to neighboring cells to form multinucleate cells. e) migration of the apoptotic cells from the tissue to the lymphatic system to be flushed out.Gram negative cell walls contain lipopolysaccharide (LPS) as a unique component. All of the following apply to LPS EXCEPT O LPS is composed of mycolic acids that protect the cell from phagocytosis LPS is a PAMP that can be recognized by toll-like receptors (TLRS) as a foreign molecule fo rphagocytosis O LPS can be a target for specific IgG for ADCC-opsonization LPS can be recognized by B cells in the aosence of MHC molecules All of the answers apply, no exception O LPS is found in the outer membrane of Gram negative cells
- IgE binds to which of these cell types to trigger allergic responses? O 1) B cell O 2) neutrophil O 3) mast cell 4) MonocyteDecreasing the amount of cytokine produced by the body would most directly prevent what event during the progression of COVID-19 in its host? A). Early viral infection of host cells. B). Replication of infected cells. C). Excessive damage to lung cells by the hot immune system. D). Transmission of the virus from one host to another.A patient develops a blood infection with a capsule-producing strain of E. coli. Phagocytosis by macrophage will be essential to destroy the bacteria and resolve the infection. Which of the following will be dirertly required to allow ADCC-opsonization of the encapsulated E. coli: O Toll-like receptor (TLR)-induced secretion of tumor necrosis factor alpha O Release of C3a to the extracellular fluids O Presence of MHC II on the surface of the macrophage O Presence of IgG receptors (Fc-gamma-R) on the macrophage All of the answers apply