Lane 1: A normal individual Lane 2: An individual homozygous for a deletion that removes the -50 to -100 region of the gene that encodes this mRNA Lane 3: An individual heterozygous in which one gene is normal and the other gene had a deletion that removes the -50 to -100 region Lane 4: An individual homozygous for a mutation that introduces an early stop codon into the middle of the coding sequence of the gene Lane 5: An individual homozygous for a three-nucleotide deletion that removes the AG sequence at the 3' splice site

If a section of a chromosome is heavily methylated, which of the following is likely to be true? Group of answer choices That portion of the chromosome is transcriptionally active That portion of the chromosome consists of euchromatin That portion of the chromosome is transcriptionally quiet RNA polymerase will have easy access to the DNA in that region

1. Bradykinin peptide: a) The sequence of the gene that encoded it, indicating with different colors, the direction, its components and the part of the cell where it occurs with the name of this stage. b) The sequence of the mature mRNA, indicating with different colors the structure of its components and the site of the cell with the name of the stage where it occurs. c) Mention the site of the cell where the bradykinin peptide was synthesized. d) In the DNA sequence make a point mutation by substitution, indicate with a different color the site and the effect it will have on the respective codon and to which amino acid it will be translated. 2.   Based on the answer in (a), use the DNA sequence of bradykinin to describe the outcome of the replication step. 5.   You have the picture of DNA transcription and mRNA translation between prokaryotic and eukaryotic cells.Instruction: Make a comparative chart showing the differences between the two cells. (image) 7. Methylations. Describe…

a. How can a single eukaryotic gene give rise to several different types of mRNA molecules?b. Excluding the possible rare polycistronic message,how can a single mRNA molecule in a eukaryoticcell produce proteins with different activities?

Unanswered gene has three exons that are 140, 230, and 130 bp, respectively. Intron 1 is 125 bp and intron s 95 bp. How long is the properly spliced mature RNA transcript? 220 500 720 1500

Discuss the consequences of a germ-line versus a somatic mutation.

please do the recent ones first

Which of the following mutations in the protein-coding region of a gene is more likely to lead to complete loss of function of the encoded protein: an insertion of six nucleotides or a deletion of two nucleotides? Briefly explain your answer.

Immunostaining was used to investigate the expression of the Fibrillin 1 gene in muscle fibres. Two antibodies were used, Antibody A binds to a muscle membrane protein that is unrelated to Fibrillin. Antibody B binds to the N terminus of Fibrillin 1, whilst Antibody C binds to the C terminus of Fibrillin 1. What is the best explanation for the staining pattern see in the following figure Antibody B Antibody A Antibody C

A gain-of-function mutation is one in which a gene is expressed at the wrong time or in the wrong type of cells. Which of the following mutations could result in a gain of function of one or more genes? Duplication Translocation Deletion Substitution All of these choices are correct