KSS (Kearns–Sayre syndrome), is caused by a mutation in the mitochondrial DNA. A normal woman marries a man with KSS. What percentage of their offspring would be expected to have KSS syndrome? 0% 50% 100% only the males will inherit this disorder

I am having trouble solving this problem sets about sex-linked inheritance. Hemophilia is a recessive X linked genetic disorder (refer to BIOL 40 B), a medical condition in which the ability of the blood to clot is severely reduced, causing the sufferer to bleed severely from even a slight injury. The condition is typically caused by a hereditary lack of a coagulation factor, most often factor VIII or factor IX (refer to Bio 40 B Textbook chapter 19 on Blood). Based on a recent study that used data collected on patients receiving care in federally funded hemophilia treatment centers during the period 2012-2018, as many as 33,000 males in the United States are living with the disorder. Males inherit the X chromosome from their mothers and the Y chromosome from their fathers. Females inherit one X chromosome from each parent. Thus, males can have a disease like hemophilia if they inherit an affected X chromosome that has a mutation in either the factor VIII or factor IX gene. Females can…

Please answer attached question.

Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb too much iron from the diet. This excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. A man who had hemophilia (an X-linked recessive genetic disorder), married a woman who had no family history of hemophilia whatsoever.  The couple had consulted a genetic counselor when they first contemplated having children due to concerns that their future children might have hemophilia.  Genetic testing of both future parents revealed that the husband did, in fact, possess the Hemophilia A allele but his wife was completely normal with respect to hemophilia.  Much to their shock, their first child, a daughter, had a mild blood clotting disorder.  Karyotyping was performed to determine whether this daughter had an…

Neural Tube Defects (NTDs) are one of the most severe congenital malformations. A study was conducted to determine whether supplementation with folic acid or a mixture of seven other vitamins (A, D, B1, B2, B6, C, and nicotinamide) around the time of conception could prevent neural tube defects. A total of 1817 women at high risk of having a pregnancy with a neural tube defect (because of a previous affected pregnancy) were allocated at random to one of four groups: 1) folic acid; 2) other vitamins; 3) both; 4) neither. 1195 had a completed pregnancy; 27 of these had a known neural tube defect, 6 in the folic acid groups and 21 in the two other groups.  This resulted in a risk ratio= 0.28. What type of study design is this? a) Case-control b) Randomized controlled trial c) Prospective cohort d) Retrospective cohort

Please explain why Huntington’s Disease is a dominant allele, but its occurrence is very low in the population.

Jonah and Jana are siblings. Jonah has the genetic disorder cystic fibrosis, caused by inheriting two mutant alleles of the CFTR gene (the gene that when mutant causes cystic fibrosis) - one allele was inherited from each parent. Jana does not have cystic fibrosis. Which of the following statements is/are true? Jana does not have the CFTR gene. Jana has two copies of the CFTR gene. Jana has at least one copy of the non-mutant allele of the CFTR gene. Jana has two copies of the mutant allele of the CFTR gene.