Km of muscle hexokinase is _________ than that of liver glucokinase enzyme. As a result, the velocity of the reactions catalyzed by hexokinase is _________ as compared to glucokinase at a physiological concentration of 5mM glucose. Lower; Low Higher; low Lower, High Higher; High

Falling energy levels increase the cellular AMP/ATP ratio, priming AMPK for activation by the liver kinase B1 (LKB1). AMPK phosphorylates multiple targets with the cumulative effect of blocking anabolic reactions and stimulating energy-generating catabolic pathways. Group of answer choices True False

Which of the following conditions will produce active glycogen phosphorylase? AMP АТР Phosphorylation of Serine 14 Glucose Glucose-6-Phosphate Phosphorylation of Serine 14 and AMP Phosphorylation of Serine 14 and ATP

Which of the following is TRUE? O Both AMP and ADP are negative regulators of glycogenolysis. ATP shifts the curve of glycogen phosphorylase to the left. O Citrate binds covalently to acetyl CoA carboxylase. Phosphofructokinase-1 is an allosterically regulated enzyme in glycolysis. The carnitine shuttle is positively regulated by Malonyl CoA.

After infection, some T cells (a particular type of immune cell) may persist as memory T cells (TMcells). When they re-encounter the same pathogen, T­M­ cells rapidly divide to produce more T cells to help fight off the infection. This rapid cell division requires substantial energy. One way that this energy is provided to TMcells is via increased activity of the ETC. One standard type of experiment for analyzing oxidative metabolism is measuring the oxygen consumption rate OCR in the presence of different compounds. The lines indicate the time at which the different ETC/OxPhos inhibitors were added. Note that the inhibitors are never removed. Complete the table below. Time Period 1 2 3 4 Inhibitor added None Oligomycin (inhibits ATP Synthase) FCCP (Uncoupler) Rotenone + Antimycin (Complexes I and III) Can electrons flow? If so, from which compound to which compound? If not, what is preventing it?         Can H+move through the membrane? If so,…

The average cell at rest hydrolyzes 10,000,000 ATP molecules per second.You are studying the stem cell population found in intestinal Crypts.In the intestine there are s total 5*1011 cell.The stem cells have a 85% higher metabolism than an average resting cell.ATP hydrlysis yield 7.4 kCal/Mole ATP(Avogadro's number is 6.023*1023) How many Kcal of energy are used per day by this population of cells? Assuming 32 ATP per glucose oxidative metabolically how many moles of glucose are consumed per day?

In the three different energy systems, name the energy compounds, and which systems are stressed during exercise of different intensities

n your own words and with your own diagrams, describe the catalytic reaction mechanism of the enzyme acetylcholinesterase. Discuss the functional roles of each member of the catalytic triad plus whatever other residues that you find important. Describe the actual movements of protons, and the making and breaking of bonds. What types of chemistries is the enzyme using? (what is the enzyme doing, in term of reaction

An individual developed a condition characterized by progressive muscular weakness and aching muscle cramps. Fasting. exercise, and a hiyh-fat diet aggravated the symptoms. The homogenate of a skeletal muscle specimen from the patient oxidized added oleate more slowly than did control homogenates consisting of muscle specimens from healthy individuals. When the pathologist added carnitine to the patient's muscle homogenate, the rate of oleate oxidation equaled that in the control homogenates. Based on these results, the attending physician diagnosed the patient as having a carnitine deficiency. Why did added carnitine increase the rate of oleate oxidation in the patient's muscle homogenate? The carnitine shuttle transports coenzyme A across the mitochondrial membrane to aid in fatty acid oxidation. Carnitine is a required cofactor for the fatty acid oxidation enzyme acyl-CoA dehydrogenase. The carnitine-mediated entry of fatty acids into mitochondria is the rate-limiting step in fatty…

When does the bulk of ATP regeneration primarily occur? At rest During interval training In the glycolytic system With gluconeogenesis