IX. Insulin, a hormone vital in blood sugar regulation and having a polypeptide chain with disulfide linkages, loses its regulatory activity when heated at nearly 100°C for 5-10 minutes. Explain the molecular basis of this observed thermal property of insulin relative to its native structure and function. Use not more than 10 short sentences for this item
Q: What is measured at the A260 absorbance values?
A: DNA and RNA absorbs UV light due to heterocyclic rings of the nucleotides that is present in the nuc...
Q: sub= 18 help
A: The reaction given in the question involves the conversion of dihydroxyacetone phosphate to glyceral...
Q: 1. Based on your knowledge about gums and mucilages, how will you differentiate resins from them? (O...
A: Q. 1. Mucilages are generally normal products of metabolism (physiological products), formed within ...
Q: Amino acids are classified according to the R group linked at the carboxyl group. a. True b. False
A: Amino acids are the monomeric units of the proteins. Generally , 20 types of amino acids are found i...
Q: Which of the following amino acid-classification pair is incorrect? O Lysine-basic amino acid O Phen...
A: Amino acids are building blocks of protein. All Amino acids consist of - COOH ( carboxyl group ) and...
Q: Modified true or false. Write the correct answer if the underlined word is false.
A: Any organic molecule that consists of a basic amino group, an acidic carboxyl group, and a distinct ...
Q: Experimental results describing a protein's amino acid composition are useful for estimating the mol...
A: Proteins are biological macromolecules composed of amino acids linked together by peptide bonds. The...
Q: Tertiary structures refer to the three-dimensional arrangement of every atom in the molecule. On the...
A: The proteins have several levels of structural organizations that ultimately determine the final fol...
Q: What are the factors necessary for the rapid absorption of sugars?
A: Carbohydrates are defined as the poly hydroxy aldehydes or ketones with an emperical formula CX(H2O)...
Q: Below is kinetic data obtained for an enzyme-catalyzed reaction. The enzyme concentration is fixed a...
A: Enzymes are the protein molecules that increase the rate of reaction by decreasing the activation en...
Q: What is the best interpretation for the results below? Test/s Results Ninhydrin Fohl's Test Biuret T...
A: Proteins are composed of twenty standard amino acids attached together via peptide bonds. These twen...
Q: (a) Vanillic acid is a phenolic compound found in vanilla and many other plant extracts. It is a fla...
A: According to shikimate pathway, Phenylalanine goes through biosynthesis wherein p-coumaroyl coenzym ...
Q: What type of linkage/s are present in Lactose? a(1 → 4) only O B(1→4) only O a, B(1→ 2) only O a (1→...
A: Lactose is known also as milk sugar since it is found in milk of mammals. It is important as an inf...
Q: Four amino acid samples were subjected to a reverse-phase chromatography set up and yielded the foll...
A: Amino acids differ from each other on the basis of their side-chain properties. Some amino acids are...
Q: The enzyme phosphofructokinase transfers a phosphate from ATP to the hydroxyl group a C1 of fructos...
A: Substrate specificity - The particular enzyme acts only on it's specific substrate and binds only to...
Q: What is the difference between the two salt precipitation methods: salting in and salting out? Gro...
A: SAlting out is a method generally used in purification of molecules depending on their solubility a...
Q: The proofreading of DNA is essential for faithful replication. True False
A: Introduction - DNA polymerase 1 and 2 are known to excise erroneous nucleotides before the introduc...
Q: Click on the scheme on a functional group that has positive charge at pH 10.0: H2N. NH2 NH H2N COOH
A: The pKa of the ionizable groups of amino acids, play an important role in determining the net charge...
Q: Calculate the pH of a solution containing 0.0314 M malic acid and 0.020 M potassium hydrogen malate....
A: Given Values: Ka1 = 3.48×10-4 Ka2 = 8×10-6 Conc. of malic acid = 0.0314 M Conc. of potassium hydroge...
Q: Phosphocreatine (G0ʹ = -43.1 kJ/mol) has a higher phosphoryl group transfer potential than ATP (G0...
A: Hi! Since you have posted multiple questions and have not mentioned which to answer, we shall answer...
Q: In a solution at physiological pH, the side chain of a polar basic amino acid bears a charge. Positi...
A: An amino group and an acid group are present in organic molecules called amino acids. Amino ac...
Q: MULTIPLE CHOICE 1. High density lipoproteins is an example of which kind of protein? A. Regulatory...
A: Proteins are composed of twenty standard amino acids attached together via peptide bonds. These twen...
Q: All coenzymes are cofactors. However, not all cofactors are coenzymes. O Both statements are incorre...
A: Enzymes require cofactors for their activity. It means in the absence of its specific cofactor an en...
Q: Given the chromatogram below in a normal phase, which samples would be the most polar? A O Samples C...
A: The process of separation of molecules in normal phase depends on the distribution of particles betw...
Q: draw an isomer of the triglyceride in sunflower seed oil. Show the reaction and write out the produc...
A: Hydrogenation is the process of chemical modification that is performed by addition of hydrogen to (...
Q: Given a tripeptide Cys-His-Lys, Cys: Pk1 = 1.5; Pk2 = 10.8; PkR = 8.5 His: Pk1 = 1.6; Pk2 = 9.0; PkR...
A: Hi. Thank you for the question, As per the honor code, we are allowed to answer three sub-parts at a...
Q: H* ions generated by reactions in the electron transport chain, as well as H* ions present in the ma...
A: The ETC is an ordered arrangement of electron carriers in the inner mitochondrial membrane. They are...
Q: State Two points to support the statement below, using adequate and sufficient information to clearl...
A: Humans have 13 vitamins, which are categorized based on their solubility. Nine vitamins are water-so...
Q: Which of the following is the odd one out? Kinases Oxidoreductases Isomerases Lyases Translocases
A:
Q: which functional group remains charged at pH of 9. „NH2 H2N COOH
A: The pKa of the ionizable groups on an amino acid determines the net charge of the amino acid. Since ...
Q: Having the ability to degrade the DNA allows the DNA polymerase to perform its job properly and effi...
A: DNA replication is a complex process of producing copies of the entire chromosome using the templa...
Q: A) Why most therapeutic inhibitors (prescription medications) that are enzyme inhibitors function th...
A: A competitive inhibitor is any compound that bears a structural resemblance to a particular substrat...
Q: Provide an example where "gradient" acting as a force and driving life
A:
Q: Which of the following is NOT true regarding E. coli replication on the lagging strand? initially...
A: In molecular biology, DNA replication is the process of making two identical DNA molecules from one ...
Q: what are miscellaneous lipids?
A: Lipids get classified as - Simple lipid Compound lipid Derived lipid Miscellaneous lipid
Q: List the systematic classification of enzymes according to the Enzyme Commission indicating the clas...
A: A protein or RNA produced by living cells that is highly selective and catalytic to its substrates i...
Q: Differentiate fertilized and unfertilized egg of Ascaris. Differentiate male and female worm of Ancy...
A: Introduction: Ascaris lumbricoides is a roundworm of man and it is the largest intestinal nematode p...
Q: Which of the following statements about glucose metabolism is correct? A. Glucagon increases the ...
A: Glucose metabolism involves many pathways which are Glycolysis in which glucose is broken down into ...
Q: Give the similarities and differences of the gel filtration and isoelectric precipitation in terms o...
A: Protein Purification: Modern protein science lab and related industries overexpress target protein i...
Q: Why Sexual is the most important type of variation in human?
A: Sexual variation causes genetic diversity in humans . Genetic diversity is important because it give...
Q: (iv) Consider the molecule 1 being derivatized to yield molecule 2. How would you expect AG for the ...
A: Biomolecules are the molecules involved in several biochemical pathways and also part of important b...
Q: CH-OH НО OH What is the name of this structure? OH OH alpha-D-gulopryranose O beta-L-gulofuransone O...
A: Pyranose : Has 6 membered ring with 5 carbon atoms and 1 O atom Furanose : Has 5 membered ring with ...
Q: Which of the following pairs of carbohydrates are disaccharides? O sucrose and maltose O cellobiose ...
A: Carbohydrates are composed of carbon, oxygen, and hydrogen which are connected by the glycos...
Q: Which of the following is an indication that a glycerol molecule reacted with potassium hydrogen sul...
A: When glycerol molecules reacts with potassium hyderogen sulphate, it causes the dehydration of glyce...
Q: How to identify the Vmax and the Michaelis constant (Km) in an enzyme kinetics graph?
A: Vmax and KM are the two parameters that define the kinetic behavior of an enzyme as a function of [S...
Q: Explain what is meant by the term, “high energy compound”. Name a thioester molecule that is common...
A: “Since you have asked multiple questions, we will solve the first question for you. If you want any ...
Q: Do you feel that laboratory animals should be used in experiments in toxicology? Why or why not?
A: People and our quality of life benefit from research using laboratory animals. Most people on the ea...
Q: Which enzyme would have the greatest catalytic efficiency? a) Km 20 nM; kcat 50 s-1 b) Km 0.04 uM; ...
A: [S] is Substrate concentration V is velocity of reaction Kcat - Catalytic constant(Turnover number...
Q: In order to replicate both strands of DNA SIMULTANEOUSLY , E. coli bacteria folds or loops one stran...
A: Replication is the process by which new strands are synthesized complimentary to their parent strand...
Q: The porosity of the PAGE gel is determined by the ratio of acrylamide and the amount of (TEMED, bis-...
A: Introduction: Polyacrylamide gel electrophoresis is a subtype of gel electrophoresis whereby normal ...
Step by step
Solved in 2 steps with 1 images
- IX. Insulin, a hormone vital in blood sugar regulation and having a polypeptide chain with disulfide linkages, loses its regulatory activity when heated at nearly 100°C for 5-10 minutes. Explain the molecular basis of this observed thermal property of insulin relative to its native structure and function. I--A plant breeder has developed a new frost-resistant variety of tomato that contains higher levels of unsaturated fatty acids in membrane lipids than those found in standard tomato varieties. However, when temperatures climb above 95°F, this frost-resistant variety dies, whereas the standard variety continues to grow. Provide a likely explanation of the biochemical basis of increased tolerance to cold and increased susceptibility to heat of this new tomato variety.High blood levels of triacylglycerides are associated with heart attacks and strokes. Clofibrate, a drug that increases the activity of peroxisomes, is sometimes used to treat patients with such a condition. What is the biochemical basis for this treatment?
- Name: Date: Year/Section: Score: ACTIVITY 5.1.1 Determine the catalytic power of jack bean urease in catalyzing the hydrolysis of urea given the following conditions: At 20C, the rate constant for enzyme-catalyzed reaction is 3x104/sec The rate constant for the uncatalyzed hydrolysis of urea is 3x10-10/sec. ACTIVITY 5.1.2 Give examples of enzymatic reaction for each type of specificity 96 Copyright 2019. All Rights Reserved. 2--------44. Effects of clofibrate. High blood levels of triacylglycerides are associated with heart attacks and strokes. Clofibrate, a drug that increases the activity of peroxisomes, is sometimes used to treat patients with such a condition. What is the biochemical basis for this treatment? Please Demonstrate and explain.Explain the metabolism, biochemical importance and inborn error of Glycine Phenylalanine, tyrosine - Tryptophan Sulphur containing amino acids.
- Insulin dependent diabetes is often accompanied by high levels of triacylglycerols in the blood. Suggest a biochemical explanation.. Explain what is meant by the term, “high energy compound”. Name a thioester molecule that is commonly found in biochemical reactions. Explain why thioesters are “high energy” compounds. Describe the molecular structure of cellulose. How does this structure explain why cellulose forms strong fibers? Explain why digestion of cellulose takes a long time even when catalyzed by an enzyme. The enzyme phosphofructokinase transfers a phosphate from ATP to the hydroxyl group a C1 of fructose. Similar to fructose, water also has a hydroxyl group and the concentration of water is much higher than that of fructose. Explain why the phosphate is transferred to fructose and not to water.A 68 year old retired construction worker is referred to the dialysis clinic following a recent diagnosis of chronic kidney disease due to a prolonged use of of the NSAID Ibuprofen. Explain the biochemical basis of NSAID nephropathy?
- One mechanism by which lead exerts its poisonous effect on enzymes can be stopped by chelation therapy with EDTA. Describe this type of lead poisoning and explain why it is reversible.After determining the optimum pH, you are now tasked to determine the inhibitory effects of acarbose, a known anti-diabetic drug which acts an inhibitor of alpha-glucosidase, an intestinal enzyme that hydrolyzes starch to release glucose for absorption and energy usage of the body. You studied the rates of the enzyme at different glycogen concentrations with and without the presence of 0.10 mM acarbose. Below is the summary for this procedure. a) What is the Vmax, in arbitrary units, of the uninhibited reaction (without acarbose)? b) What is the KM , in mM, of the uninhibited reaction (without acarbose)? c) What is the type of inhibition?Determine the molecular weight of the protein glycogen phosphorylase which is composed of 842 amino acids.