In order for transcription to begin, the DNA-duplex must be "opened" to allow RNA polymerase access to the unwound segment. All help in the ease of the "opening" of DNA-duplex EXCEPT: A. low melting temperature, TM, in the Pribnow box. B. G - C rich DNA duplex. C. negative supercoiling. D. binding of RNA polymerase σ-subunit.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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In order for transcription to begin, the DNA-duplex must be "opened" to allow RNA polymerase access to the unwound segment. All help in the ease of the "opening" of DNA-duplex EXCEPT:

A. low melting temperature, TM, in the Pribnow box.
B. G - C rich DNA duplex.
C. negative supercoiling.
D. binding of RNA polymerase σ-subunit.
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