In a particular country in sub-Saharan Africa, a medical study revealed that 0.075% of the country's population are suffering from sickle-cell anaemia. Sickle cell disease is caused by a mutation in the haemoglobin-Beta gene found on chromosome 11. Sickle cell anaemia is controlled by a pair of alleles, H and h, where the individuals with the illness have the homozygous recessive genotype; those with normal red blood cells have the alternative genotype. Using the Hardy-Weinberg's equation, calculate the percentage of the population of the two genotypes for normal blood cells. In a few remote areas in that country, the percentage of sickle cell anaemia reaches as high as 5%. Calculate the percentage of homozygous and heterozygous individuals with the normal blood cells and find the ratio for both phenotypes. Discuss whether blood cells go through mitosis.

Human Anatomy & Physiology (11th Edition)
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Question 1
In a particular country in sub-Saharan Africa, a medical study revealed that
0.075% of the country's population are suffering from sickle-cell anaemia. Sickle
cell disease is caused by a mutation in the haemoglobin-Beta gene found on
chromosome 11. Sickle cell anaemia is controlled by a pair of alleles, H and h,
where the individuals with the illness have the homozygous recessive genotype;
those with normal red blood cells have the alternative genotype.
Using the Hardy-Weinberg's equation, calculate the percentage of the population
of the two genotypes for normal blood cells.
In a few remote areas in that country, the percentage of sickle cell anaemia reaches
as high as 5%. Calculate the percentage of homozygous and heterozygous
individuals with the normal blood cells and find the ratio for both phenotypes.
Discuss whether blood cells go through mitosis.
Transcribed Image Text:Question 1 In a particular country in sub-Saharan Africa, a medical study revealed that 0.075% of the country's population are suffering from sickle-cell anaemia. Sickle cell disease is caused by a mutation in the haemoglobin-Beta gene found on chromosome 11. Sickle cell anaemia is controlled by a pair of alleles, H and h, where the individuals with the illness have the homozygous recessive genotype; those with normal red blood cells have the alternative genotype. Using the Hardy-Weinberg's equation, calculate the percentage of the population of the two genotypes for normal blood cells. In a few remote areas in that country, the percentage of sickle cell anaemia reaches as high as 5%. Calculate the percentage of homozygous and heterozygous individuals with the normal blood cells and find the ratio for both phenotypes. Discuss whether blood cells go through mitosis.
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