Huntington disease is a rare fatal, degenerative neurological disease in which individuals start to showsymptoms in their 40s. It is caused by a dominant allele. Joe, a man in his 20s, just learned that his fatherhas Huntington disease.a. What is the probability that Joe will also developthe disease?b. Joe and his new wife have been eager to start afamily. What is the probability that their first childwill eventually develop the disease?

Huntington disease is a rare fatal, degenerative neurological disease in which individuals start to showsymptoms in their 40s. It is caused by a dominant allele. Joe, a man in his 20s, just learned that his fatherhas Huntington disease.a. What is the probability that Joe will also developthe disease?b. Joe and his new wife have been eager to start afamily. What is the probability that their first childwill eventually develop the disease?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter5: The Inheritance Of Complex Traits

Section: Chapter Questions

Problem 23QP: If diseases such as cardiovascular disease (hypertension and atherosclerosis) are familial, is this...

See similar textbooks

Similar questions

Duchenne muscular dystrophy is sex linked and usuallyaffects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brotherhas Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’sdisease, what is the probability that you have receivedthe allele?c. If your father’s brother had the disease, what is theprobability that you have received the allele?
Huntington disease is a rare dominant condition in humans that results in a slow but inexorable deteriorationof the nervous system. The disease shows what mightbe called age-dependent penetrance, which is to saythat the probability that a person with the Huntingtongenotype will express the phenotype varies with age.Assume that 50% of those inheriting the HD allele willexpress the symptoms by age 40. Susan is a 35-yearold woman whose father has Huntington disease. Shecurrently shows no symptoms. What is the probabilitythat Susan will show symptoms in five years?
Huntington diseases is a rare fatal, degenerative neurological disease in which individuals start to show symptoms in their 40s. It is caused by a dominant allele. Joe, a man in his 20s, just learned that his father has Huntington disease.a. What is the probability that Joe will also develop the disease?b. Joe and his new wife have been eager to start a family. What is the probability that their first child will eventually develop the disease?
a human disease known as cystic fibrosis is inherited as a recessive trait.Two unaffected individuals have a first child with the disease. What isthe probability that their next two children will not have the disease?
Hemochromatosis is an inherited disease caused by arecessive allele. If a woman and her husband, who are bothcarriers, have three children, what is the probability of eachof the following?(a) All three children are of normal phenotype.(b) One or more of the three children have the disease.(c) All three children have the disease.(d) At least one child is phenotypically normal.(Note: It will help to remember that the probabilities of allpossible outcomes always add up to 1.)
Huntington disease is a rare dominant trait that causes neurodegeneration later in life. A man in his thirties, who already has threechildren, discovers that his mother has Huntington disease thoughhis father is unaffected. What are the following probabilities?A. That the man in his thirties will develop Huntington disease.B. That his first child will develop Huntington disease.C. That one out of three of his children will develop Huntingtondisease.
Duchenne muscular dystrophy is sex linked and usually affects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brother has Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’s disease, what is the probability that you have received the allele?c. If your father’s brother had the disease, what is the probability that you have received the allele?
A young couple went to see a genetic counselor because each had a sibling with cystic fibrosis. (Cysticfibrosis is a recessive disease, and neither member ofthe couple nor any of their four parents is affected.)a. What is the probability that the female of thiscouple is a carrier?b. What are the chances that their child will havecystic fibrosis?c. What is the probability that their child will be acarrier of the cystic fibrosis disease allele?
Piebald spotting is a condition found in humans inwhich there are patches of skin that lack pigmentation. The condition results from the inability ofpigment-producing cells to migrate properly duringdevelopment. Two adults with piebald spotting haveone child who has this trait and a second child withnormal skin pigmentation.a. Is the piebald spotting trait dominant or recessive?What information led you to this answer?b. What are the genotypes of the parents?
A recently married man and woman discover that eachhad an uncle with alkaptonuria (black urine disease), arare disease caused by an autosomal recessive allele of asingle gene. They are about to have their first baby. Whatis the probability that their child will have alkaptonuria?
A woman with achondroplasia (a dominant form of dwarfism) anda phenotypically unaffected man have seven children, all of whomhave achondroplasia. What is the probability of producing such afamily if this woman is a heterozygote? What is the probabilitythat the woman is a heterozygote if her eighth child does not havethis disorder?
Both members of a couple know that they are carriers of the cysticfibrosis allele. None of their three children has cystic fibrosis, but anyone of them might be a carrier. The couple would like to have a fourthchild but are worried that he or she would very likely have the disease,since the first three do not. What would you tell the couple? Would itremove some uncertainty from their prediction if they could find outwhether the three children are carriers?