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How would you demonstrate that a neuron or class of neuron is an essential member of a central pattern generator?
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- For you to see the words on your compute, quite a few different types of neurons are required. what types of neurons are involved in signal transmission for you to see the words? Describe all the neural structures fro required for seeing.Demyelination is the loss of myelin from neurones that are normally myelinated. Multiple sclerosis is a disease in which demyelination occurs in neurones involved in coordinating muscle movement. Using your knowledge of nerve impulse generation and propagation, explain how nerve impulse generation and propagation would be affected in people who have multiple sclerosis. The explanation needs to be in the form of a step by step sequence of annotated drawings. This could be in the form of an annotated cartoon/picture strip. Compare this to nerve impulse generation and propagation in an individual who does not have multiple sclerosis.State the all-or-none principle as it pertains to actionpotentials.
- Using the neurons below, how can you decrease the connection strength (amplitude of EPSP) onto the test cell below? You can only change the properties of the blue neuron. How could you change the properties of the blue neuron to increase the connection strength onto the test cell? What type of plasticity is this? Now, briefly explain how the properties of synaptic plasticity could result in “learned” behaviors such as stopping at a stop sign while driving.An effector neuron is a motor neuron that transmits impulses from the CNS to an effector (muscle or gland).In an experiment, it was determined that the effector neuron for muscle fibre 1 had a threshold level of –5 mV. The effector neuron for muscle fibre 2 had a threshold level of –16 mV. An electrical probe was used to stimulate these two effector neurons of the muscle fibres. Which of the following rows correctly identifies the reaction of each muscle fibre based on the applied stimulus voltage? Stimulus Voltage Muscle Fibre 1 Muscle Fibre 2 –20 mV Relaxed Contracted b. Stimulus Voltage Muscle Fibre 1 Muscle Fibre 2 –20 mV Contracted Relaxed c. Stimulus Voltage Muscle Fibre 1 Muscle Fibre 2 –10 mV Contracted Relaxed d. Stimulus Voltage Muscle Fibre 1 Muscle Fibre 2 –10 mV Relaxed ContractedIf TTX (tetrodotoxin) selectively binds voltage gated Na+ channels, and you tag TTX with a fluorescent marker and then you use it as a probe to label voltage-gated Na+ channels in various neurons in the CNS, would you expect the pattern of fluorescence to be different between myelinated and nonmyelinated axons? If so, how? If not, why not?
- Draw a simple schematic of a neuron and label its parts. Where does “information” usually go in and through which structure is it passed on? Where is the action potential generated?What do you mean by neurospora? Give some examples.Parkinson's Disease Parkinson's disease is neurodegenerative disorder that affects movement. Most people affected with Parkinson's disease demonstrate rigidity, slow movement, and shaking. The symptoms of Parkinson's disease occur when the cells that produce dopamine neurotransmitters die in the brain. Explain how the signal transmission at a synapse in an individual with Parkinson's disease is different than an unaffected individual. Describe the normal process of signal transmission at a synapse. Start with the arrival of an action potential at the axon terminal and include the name of the neurotransmitter that is affected by Parkinson's disease. Explain how the process is different in individuals affected with Parkinson's disease.
- Help meWhen expert pianists listen to familiar, well-practiced music, they imagine the finger movements, and the finger area of their motor cortex becomes active, even if they are not moving their fingers (Haueisen & Knösche, 2001). If we regard those neurons as another kind of mirror neuron, what do these results imply about the origin of mirror neurons?Which types of patch clamp technique should be used if you want to determine if a particular compound is influencing synaptic transmission presynaptically or post synaptically?