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- Briefly (list in bullet points) what are the FIVE stages of Protein synthesis. Why do you suppose incidences of mutations in enzymes involved in these processes are extremely rare in people — affectingADP ribosylation is one example of post-translational modification of an enzyme. Which statements about the process is true? ADP ribosylation will affect protein folding because of the addition of a large molecule ADP ribose can be added to the amine group of lysine or glutamine The ending of DNA around histones in the nucleus is altered by the ADP -ribosylation of the histone proteins in cancer cells ADP ribosylation requires ADP and the target protein as the substrates in the ADP ribosylation ADP ribosylation of phosphoinositol is an important step in signaling through a G protein-coupled receptor pathway.If an extra nucleotide is inserted in the first exon of the beta globin gene, what effect will it have on the amino acid sequence of the globin polypeptides? Will the globin most likely be fully functional, partly functional, or nonfunctional? Why?
- 1. True or false for these statements: a. ubiquitin molecule signals that a protein is ready to be transported to the endoplasmic reticulum b. In the ribosome during translation, the incoming tRNA will transfer its amino acid to the outgoing tRNA c.Folding of nascent or new proteins occurs after the full-length polypeptide chain has been separated from the ribosome after translation d. A signal peptide may or may not be degraded once it has guided the polypeptide to the endoplasmic reticulum(a.) When a mutation occurs to the given sequence of DNA, it will be; 5' CTATAAGGCGCAAATTCCTGCCAT 3' Then the mRNA sequence will be, 5' GAUAUUCCGCGUUUAAGGACGGUA 3' Amino acids - (Asp Leu Pro Arg Leu Arg Thr Val) (b.) When a mutation occurs to the given sequence of DNA, it will be; 5' CTATAAGGCGGAAATCCCTGCCAT 3' Then the mRNA sequence will be, 5' GAUAUUCCGCCUUUAGGGACGGUA 3' Amino acids - (Asp Leu Pro Pro Leu Gly Thr Val) (c.) When a mutation occurs to the given sequence of DNA, it will be; 5' CTATAAGGCTCAAATCCCTGCCAT 3' Then the mRNA sequence will be, 5' GAUAUUCCGAGUUUAGGGACGGUA 3' Amino acids - (Asp Leu Pro Ser Leu Gly Thr Val) (d.) When a mutation occurs to the given sequence of DNA, it will be; 5' CTATAAGGCGCAAATCCCTCCAT 3¹ Then the mRNA sequence will be, 5' GAUAUUCCGCGUUUAGGGAGGUA 3' Amino acids - (Asp Leu Pro Arg Leu Gly Arg).As the last sequence contains only 2 bases it will not represent any amino acid. question: Choose the types of mutations caused by the changes in parts…Phosphorylation is a very common post-translational modication (PTM) to regulate protein function. Which amino acids are most commonly regulated by phosphorylation? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a Leucine, arginine, serine. b Tyrosine, arginine, glutamine. C Serine, threonine, tyrosine. d Glutamine, arginine, tyrosine. e Serine, tyrosine, glutamine.
- 1. TRUE OR FALSE a) The genetic code in unambigous that means many codons can code for the same amino acids. b) There are no aminoacyl-tRNAs that will go to the A site of the ribosome when UGA is the codon.Hydrogen bonds are important in DNA replication and transcription. They are relatively weak chemical bonds. Why is this a desirable feature for DNA? Describe the effect (s) of changing (mutating) the promoter on the transcription of the DNA strand/gene the promoter controls. What happens to protein synthesis if a nonsense codon is inserted into the gene? Explain why a point mutation does not necessarily change the original amino acid sequence. (Explain silent mutations) Choose any pentapeptide composed of five different amino acids. List the amino acids. Present one messenger RNA codon for each amino acids and the sequence of nucleotides on the DNA that originally coded for your pentapeptide.Describe the gene and protein defects in phenylketonuria (PKU). How are these defects connected to disease symptoms?
- which of the following amino acids can undergo post-translational acetylation? A.n B.s C.k D.m10. A portion of 5'-AUGCCACGAGUUGAC-3'. What amino acid sequence does this code for? To answer the question please: I) explain what is the genetic code and list the properties of the genetic e 2) draw a diagram of protein synthesis; 3) determine which tRNA should be attached to the mRNA; 4) what is the anticodon for the very first tRNA that will attach to mRNA? mRNA molecule has the sequence anDefine transcription and translation. Give 3 ways in which they are similar and 3 ways in which they are different.
