Hematology Case Studies Case Study 1 Patient: Jane F. Age: 70 Sex: F History: Complains of trouble breathing after mild physical activity and easily fatigued. Denied hemoptysis, GI, or vaginal bleeding. Claimed diet was good, but appetite varied. Physical Exam: Other than pallor, no significant physical findings were noted. Occult blood was negative СВС 3.71 x 1012/L | 5.9 g/dL 20.9% RBC HGB НСТ 56.2 fL 15.9 pg 28.3 g/dL MCV МСH МСНС WBC 5.9 x 10/L N seg 82% L 13 1 E 4 B PLT 425 x 10%L Further Laboratory Studies Iron Studies Patient Values RI |<10 ng/mL 24 µg/dL 729 µg/dL 3% Serum Ferritin Serum Iron 12-86 65-175 250-410 TIBC Saturation 20-55

Case Study: Sarah's Immune Challenge Background: Sarah is a 35-year-old nurse who recently started experiencing unusual fatigue, joint pain, and frequent infections. She decided to consult her healthcare provider for a thorough evaluation. Medical History: Chronic sinus infections Family history of autoimmune diseases Recent exposure to a patient with tuberculosis (TB) Vital Signs: BP: 120/80 mm Hg Heart rate: 90 bpm Temperature: 100.4\deg F - Respiratory Rate: 20 breaths/min Lab Tests: Elevated white blood cell count Positive PPD skin test for TB Elevated levels of autoimmune markers Diagnosis: Sarah was diagnosed with an autoimmune disorder as well as latent TB. Interpret the graph: How do innate and adaptive immune responses vary over time? Immune Response Level Immune Response Over Time 15- 10- Days C Immune Type Adaptive Immunity Innate Immunity

C. Give the meanings of the following abbreviations 1. TPN - 2. PUD - 3. EGD - 4. IBD - BE - 5. 6. BRBPR - 7. LTFS 8. GERD - 9. HBV - 10. CT-

Patient D: 38 y/o male vegetarian. Complains of mild irritation during urination. Urine volume 1.1 liters/24 hours. Microscopic examination of urine revealed many small pyramid shaped crystals. 1) List the abnormal findings. 2) What is your diagnosis? 3) What might have caused this disease? 4) How does diet affect urine? 5) Have you ever tried drinking 12 large glasses of water in a day? Why would drinking water be helpful to this individual?