hat happens to the ends of linear chromosomes in eukaryotes during replication?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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What happens to the ends of linear chromosomes in eukaryotes during replication?
How are the ends of eukaryotic chromosomes maintained? What happens when
the process goes wrong? 

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Step 1

DNA replication in eukaryotes is a highly regulated process and usually requires extracellular signals to coordinate the specialized cell divisions in different tissues of multicellular organisms. External signals are delivered to cells during the G1 phase of the cell cycle and activate the synthesis of cyclins. Cyclins form complexes with cyclin dependent kinases, which, in turn, stimulate the synthesis of S phase proteins such as DNA polymerases and thymidylate synthase. These complexes prepare cells for DNA replication during the S phase.

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