Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Haemophilia is a genetic disorder caused by a recessive allele on the X chromosome.
A haemophilia female marries a normal male. Explain why all their sons will be haemophilia.
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- A man and woman are both heterozygous for the recessive allele that causes cystic fibrosis. What is the probability that their first two offspring will have the disorder?arrow_forwardIn which parent the chromosomal mutation occurred. Father or Mother At what stage in meiosis (I or II) the chromosomal mutation occurred see image attachedarrow_forwardA couple is going to have a baby. They are concerned about sickle cell anemia, which results from having the homozygous recessive combination of the sickle cell gene ("s"), which produces abnormal hemoglobin. Having at least one normal version of the gene ("S") results in normal hemoglobin. The woman is heterozygous, and so is the man. What alleles does mom have? What alleles does dad have?arrow_forward
- A woman is homozygous dominant for short fingers. She marries a man who is heterozygous for short fingers. What will the punnet square look likearrow_forwardMrs. and Mr. Bond have five children, Janine, Jaliyah, Joliette, Jelani and James Jr. Mr. Bond suffers from fragile X syndrome, an X-linked disease (i.e., on chromosome X) which is also dominant. Mrs. Bond is healthy. Janine, Jaliyah, Joliette and Jelani have fragile X syndrome, while James Jr. is healthy. Is there reason to suspect infidelity in this family?arrow_forwardwhat is the probability that a couple (both heterozygous for the same recessive mutation) will have two children with the disease if the couple plans to have four children in total?arrow_forward
- Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is not expressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental cross, and identify the…arrow_forwardThe pedigree chart provided below traces the occurrence of a disease through the generations of a family. Determine what type of inheritance pattern this disease has.arrow_forwardThe next three questions go together. Duchenne's muscular dystrophy (DMD) is a disease caused by a recessive allele at a gene on the X chromosome. Polydactyly is caused by a dominant allele at an autosomal gene. If a phenotypically normal woman who's father had DMD has a child with man who is heterozygous for the allele causing polydactyly but is otherwise normal, what is the probability that the child will have elther DMD or polydactyly, but not both? Part I: What is the cross? A ppxx x PpxDxD B- PPXPXX Ppx©y C- ppx"x x Ppxdy D- ppxx x PpxOy OC OB O A OD Question 11 Part II: What is the probability the child will have polydactyly but not DMD? Enter your answer to two decimal places leg. 0.88). Question 12 Part II: What is the probability that the child will have either DMD or polydactyly, but not both? Enter your answer to two decimal places (eg. 0.88).arrow_forward
- Hemophilia, disease in which the blood lacks a clotting factor, is caused by an X linked recessive gene. Joe doe not have hemophilia and Lucille is heterozygous for the condition. What is the chance that their MALE child will have hemophilia? (Note: you are calculating the probability for their MALE children only, in other words if they have 1 male child, what is the probability that he will be born with the disease?) 0% 1/4 or 25% 2/4 or 50% 3/4 or 75% 4/4 or 100%arrow_forwardWhat is the karyotype for women who have an extra X-chromosome? Discuss all the ways you can test for this abnormality.arrow_forwardDraw the punnet square and explain the resultsarrow_forward
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