For a locus with two alleles (B and b) in a population at risk from an infectious neurodegenerative disease, 16 individuals have the genotype BB, 92 individuals have Bb and 12 individuals have bb. Use the Hardy-Weinberg equation to determine whether this population appears to be evolving

The sd gene causes a lethal disease of infancy in humanswhen homozygous. One in 100,000 newborns die eachyear of this disease. The mutation rate from Sd to sd is2 × 10−4. What must the fitness of the heterozygote be toexplain the observed gene frequency in view of the mutation rate? Assign a relative fitness of 1.0 to Sd /Sd homozygotes. Assume that the population is at equilibriumwith respect to the frequency of sd.

There are two existing hypotheses for an unusually high frequency of a deleterious recessive allele in a certain population other than it is hidden in the heterozygous genotype and not exposed to selection.  Explain what these two likely hypotheses are and how you could distinguish between them based on your understanding of the applicable assumptions that are part of the Hardy-Weinberg Equilibrium Model

You sample a fruit fly (Drosophila melanogaster) population for the alcohol dehydrogenase (Adh) gene. There are two alleles, designated A₁ and A2, for this locus in this population. The data you collected is shown in this table (this is your observed data). Is this population in Hardy-Weinberg equilibrium at this locus? To save you time, I have calculated the expected number of individuals for each genotype and included them in the table. For your answer, you should provide: • an answer to the question: Is this population in Hardy-Weinberg equilibrium for this locus? • the value of your chi-square result you based this answer on (you do not have to show your calculations for the homework, but you would on an exam) • (if you say the population is NOT in HW equilibrium) an evaluation of which genotype(s) are more or less common than expected in the observed population # individuals genotype A₁A₁ # individuals genotype A₁A2 # individuals genotype A₂A2 154 117 Observed data Expected data…

Entomologists at the New York State Department of Agriculture are interested in determiningthe connection between pest insects infesting crop plants with populations of the same insect-infesting native plants in natural habitats. Long-term trapping and monitoring studies have estimated that on average 3% of the populations move between habitats (farm to natural and vis versa) each generation. A new insecticide resistance allele (∆K) has begun to increase in frequency in agricultural populations. A genotyping survey at this locus of 50 individuals in each population has revealed the following genotype counts:4a. Based on the effects of migration alone, what will the frequency of ∆K be in the forestpopulation in the next generation?   4b. If migration was acting in here without selection, what would the frequency of ΔK be in the agricultural population in the next generation?   4c. If the natural forest population was substantially larger than the agricultural population, how might…

Consider a population with  28 individuals with the genotype AA and 12 Aa individuals and 50 individuals with the genotype aa how many alleles in this population in total?

Pretend that you are comparing the actual genotype distribution for a population with the distribution of genotypes predicted by the Hardy-Weinberg theorem.  So your hypothesis is that the population is in Hardy-Weinberg equilibrium (i.e. that actual population data fit the Hardy-Weinberg expectations).  If you carry out a chisquare goodness of fit test and calculate a total chisquare value of 0.03 with 1 degree of freedom (see table), what does this mean? (select all true statements)a) The data do NOT fit the hypothesized distribution.b) The data do fit the hypothesized distribution well enough, so we accept the hypothesis at this time (i.e. we cannot reject the hypothesis). c) The probability that the data came from a population in Hardy-Weinberg equilibrium is too small, so we reject the hypothesis.d) The probability that the data came from a population in Hardy-Weinberg equilibrium is too big, so we reject the hypothesis.e) The data support Hardy-Weinberg expectations – there is no…

Consider an autosomal locus with alleles A and a. If the the allele frequencies are as follows Freq(A) = 0.4, Freq(a) = 0.6. , then what is the predicted frequency of heterozygous Aa individuals, assuming the population is in Hardy-Weinberg equilibrium? Freq(Aa) = ? Enter a number between 0 and 1, inclusive, for example 0.33