Explain the structural and functional changes in the crohn disease process that led to patient's weight loss

What explains the observation that some forms of porphyria are associated with jaundice while others are not? Some porphyrias, but not all, are due to defects in heme metabolizing enzymes that cause a buildup of bilirubin, which causes jaundice. Some porphyrias, but not all, are due to defects in heme metabolizing enzymes that increase urobilin, which is yellow and concentrated in urine. Some porphyrias, but not all, are due to defects in ABO blood type enzymes that cause a buildup of bilirubin, which causes jaundice. Some porphyrias, but not all, are due to defects in heme metabolizing enzymes that cause a buildup of biliverdin, which is green in color. 271

Describe the disease process for MG.

Explain how Vibrio cholerae causes cholera without apparent damage to the intestinal epithelium. a. This microbe attaches to the surface of intestinal epithelial cells, producing an endotoxin that causes the epithelium to secrete potassium ions. This induces small amounts of water to follow by osmosis, resulting in the watery rice-stool characteristic of the illness. b. This microbe causes destruction of the cellular structures underneath the intestinal epithelium—this is what induces the watery rice-stool characteristic of the illness. This leaves the overlying intestinal epithelium intact. c. This microbe directly invades the intestinal epithelial cells, but does not kill them. Instead, while multiplying inside them, it causes them to secrete large amounts of chloride ions. This induces water to follow by osmosis, resulting in the watery rice-stool characteristic of the illness. d. This microbe attaches to the surface of intestinal epithelial cells, producing an exotoxin…