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A: Introduction Haemoglobin is an iron-containing protein that carries oxygen in the blood.
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Discuss why it is advantageous for humans to produce
different hemoglobins at different stages of
development.
Hemoglobin is a type of a protein present in the red blood cells of vertebrates and some invertebrates. It contains iron at its center that helps in binding of oxygen. In the blood of a healthy person, the count of hemoglobin is 12-20 grams in every 100 ml.
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- Discuss what is the advantage of producing different hemoglobins at different stages ofdevelopment?Hemoglobin will bind oxygen and release CO2 in places where there is a higher concentration of O2, lower concentration of CO2, lower temperature and lower acidity (as it is in lungs) and will do the reverse – release oxygen and bind CO2 - in places where there is a lower concentration of O2, higher concentration of CO2, higher temperature and higher acidity (as it is in working muscles). True False While white blood cells never leave the circulation, red blood cells regularly leave it and travel by lymphatic system or find home in other tissues, e.g., lymph nodes, spleen, etc. True False Blood clotting (coagulation) is a complex process involving many factors and it exhibits positive feedback loops: many of the factors also stimulate production of their own precursors. B lymphocytes mature in the thymus while T lymphocytes mature in the bone marrow True False Antibodies are molecules on the surfaces of foreign…With the appearance of strong oxidizers in blood in erythrocytes one of the following substances is formed first of all: 1. carbhemoglobin 2. carboxyhemoglobin 3. oxyhemoglobin 4. methemoglobin 5. deoxyhemoglobin
- 1)Determine the properties of hemoglobin related to its chemical structure, function and color change during loading and unloading of oxygen. 2) To determine the hemoglobin content indicated by hematocrit.sickle cell disease and its variants are genetic disorders resulting from the presence of a mutated form of hemoglobin . propose a proper therapeutic strategy to ameliorate or cure this disease.(b) The diagram on the right illustrates the change in the p50 (partial pressure of O2 required to achieve 50% saturation) of hemoglobin and the 2,3-bis-phosphoglycerate (BPG) concentration in the erythrocytes of a person who spent 6 days hik- ing in the Andes Mountains of Peru. As the hiker climbs to higher and higher altitudes, the atmos- pheric pressure, including the partial pressure of O2, decreases. Yet the p50 increases, making it less favorable to achieve saturation of the hemo- globin. Explain. Pso (torr) Sea level 34 33- 32 31 30- 29 28 27 26 4530 m above- sea level (c) If individuals with the following mutant hemo- globins accompanied the hiker, evaluate the degree of respiratory distress that they would experience despite the increased erythrocyte BPG concentration. (In the ta- ble of mutants on the right, the mutation His(143)Asp, for instance, means that the His residue that occurs at se- quence position 143 on the ß-chain has been substituted by Asp.) Describe the…
- Define the term Deoxyhemoglobin?although there are other ways to prevent DVT, do you think it's vital to advocate and require the usage of sequential compression devices to maintain blood flow and prevent blood clots? pls include references.Explain how the following conditions affect the structure and function of hemoglobin. Sickle cell anemia, fetal hemoglobin and lowed pH
- Explain why erythrocytes are unique in shape and structure. Describe all the factors that make them ideal for transporting oxygen to cells.What is the importance of hemostasis in detail (blood clotting)? Explain the detail steps involved in this process.Myelodysplastic syndrome is a genetic abnormality that disrupts the ability of red blood cells (erythrocytes) to produce hemoglobin. Which cell feature is most likely disrupted? How does disruption of the normal function of this cell feature lead to a specific symptom associated with this disease? asap please.
