Describe some of the key features of cytoplasmic inheritance. Why do traits that are inherited in this way have such a wide range of phenotypes?
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- Regarding Mendelian inheritance in diploid individuals, (Read each statement carefully. Select all of the statements below that are true (that you agree with). Leave any statements that are false (that you do not agree with) un- selected.) a diploid individual receives two copies of every autosome from the previous generation. for every autosomal gene inherited by an individual, both copies can come from one parent. a diploid individual gives two copies of every autosome to a child in the next generation. to be diploid means that two independent genes are specified in the individual's genotype.Explain the term maternal inheritance? Which characters show this type of inheritance?Based on the observed inheritance pattern and ratio of phenotypes, what are the genotypes of the affected children? a) If c- = Cystic Fibrosis, the children are c-/c-. b) If c- = Cystic Fibrosis, the children are C/C. c) If c- = Cystic Fibrosis, the children are C/c-. d) If c- = Cystic Fibrosis, the children are C.
- Uniparental disomy (UPD) occurs when both chromosomes of a pair or areas from one chromosome in any individual have been inherited from a single parent. Since chromosomal numbers remain the same, cytogenetic analysis will not detect them. Hence, UPD disorders were not described until recently since molecular analysis is required to show that the two chromosomes originated from the same parent. Read recently published literature regarding UPD, and answer the following questions: What are the mechanisms that lead to UPD? Give at least 3 examples of UPD disorders and their clinical consequences: UPD Disorder OMIM # Locus Type of UPD Phenotype (include images) 1 2 3What is an example of cytoplasmic inheritance?Suppose that a grandfather, mother, and son all have the same homozygous dominant genotype for a gene that controls facial hair growth. The grandfather and son have thick beards, but the mother has no significant facial hair. What type of non-Mendelian inheritance is this? O a) Sex-influenced inheritance Ob) Sex-limited inheritance Oc) Onset of genetic expression O d) X-linked dominant inheritance
- Which of the following describes the difference between genetic maternal effect and cytoplasmic inheritance? O Progeny from a Genetic Maternal Effect cross express the phenotype of their mother's genotype, while progeny from a cytoplasmic inheritance cross share a genotype and phenotype of their mother. Progeny from a Genetic Maternal Effect cross have a phenotype that reflects their own genotype, while progeny from a cytoplasmic inheritance cross share a genotype and phenotype with their mother. Progeny from a Genetic Maternal Effect cross have the same genotype as their mother, while progeny from a Cytoplasmic Inheritance cross do not. There is no difference.Which mode of inheritance is suggested by the following pedigree? Based on this hypothesis, and assuming that the trait is rare and has complete penetrance, what are the possible genotypes of all individuals in this pedigree?Provide a proof that a different phenotype can be produced from the same genotype. What are the possible causes for this different expression? How can the different gene interactions be differentiated from each other and from the Mendelian inheritance?