Describe Pre-formulation for oral solid dosage form

Briefly explain this statement "Preformulation studies help to find the drug performance and the development of a dosage form"-explain this with different drug properties and example? Please answer at your own easy words.

Clindamycin 150mg PO every 6 hours is ordered for a child weighting 40lb 10oz. the recommended dose is 8-25mg/kg/day in three or four divided doses. On hand is Clindamycin 75mg/ml oral solution.  If safe, how many ml will you give?

The usual pediatric dose of acyclovir is 20 mg/kg administered by infusion and repeated every 8 hours. W hat would be the single dose, in milligrams, for a child weighing 33 lb? answer: 300mg   i want to know the full solution please

KCI for injection contains 40 mEq in 20 mL. An order requires 15 mEq, how many mL are needed?

Order: metoclopramide  5 mg PO Q6HPatient 30 kg; 3 years oldSupply: 5 mg/5 mLLiterature: 0.1 to 0.2 mg/kg/dose up to four times per day   Order: cefotaxime (Claraforan) 0.5 g IM Q6HPatient: 48 lbSupply: 300 mg/ reconstituted solutionLiterature: 100 to 200 mg/kg/day divided Q6H

Write the drug drug interaction between Atenolol and Ponesimod ? Please shortly write at your own words. Answer should include the effects and mechanism.

List indications for a CVAD (there are 7)

Ampicillin 150mg PO every 6 hours is order for a child that weights 12kg today. The recommended dose is 50-100mg/kg/day in four divided doses. On hand is Ampicillin 250mg/5ml.  If safe, how many ml will you give?

RNSG 1301 Pharmacology   40. You have an order to administer liquid acetaminophen 250 mg. The pharmacy has 100mg/1 mL available. How many mL will you administer? Enter number only, round to the firstdecimal place.