Deduce the sequence of a pentapeptide that contains the amino acids Ala, Glu, Gly, Ser, and Tyr, from the following experimental data. Edman degradation cleaves Gly from the pentapeptide, and carboxypeptidase forms Ala and a tetrapeptide. Treatment of the pentapeptide with chymotrypsin forms a dipeptide and a tripeptide. Partial hydrolysis forms Gly, Ser, and the tripeptide Tyr–Glu–Ala.

Q: The cleavage pattern for o-lodosobenzoate is C-terminal to tryptophan; the cleavage pattern for…

A:

Q: Pentapeptide has a sequence of APEDS Structure of pentapeptide in its proper ionization state at pH…

A: The question is based on the concept of biomolecules. We have to draw pentapeptide and calculate…

Q: Illustrate a glycosidic, peptide and a phospho-diester bond.

A: Glycosidic bond   - This bond is formed between C1 carbon atom of a monosaccharide unit and C4…

Q: What reaction conditions are needed to achieve complete peptide hydrolysis to its amino acid…

A: 1- In this question, first we will discuss about Reaction conditions for peptide Hydrolysis, then we…

Q: A tripeptide undergoes complete hydrolysis and the resulting mixture contains only phenylalanine and…

A:

Q: Show the mechanism and explain how the Ala-Val-Ile peptide bond is formed.

A:

Q: A sample of an unknown peptide was divided into two aliquots. One aliquot was treated with trypsin;…

A: The sequence of the original peptide has to be deduced.

Q: c) Show the complete reaction if Thyrosine in the aqueous basic solution d) Draw the dipeptides of…

A: Hello. Since more than one question has been asked, the first question shall only be answered in…

Q: Deduce the sequence of a heptapeptide that contains the amino acids Ala, Arg, Glu, Gly, Leu, Phe,…

A: Amino acid are the organic compounds which contains both amines  and carboxylic acids within the…

Q: Use the given experimental data to deduce the sequence of an octapeptide that contains the amino…

A:

Q: (d) A heptapeptide was found to have an amino acid composition of Asp, Leu, Lys, Met, Phe and Tyr.…

A: The question is based on the concept of biomolecules. we have been given different peptide…

Q: A normal polypeptide and a mutant of the polypeptide were hydrolyzed by an endopeptidase under the…

A: To find kind of amino acid substitution:

Q: Deduce the sequence of a heptapeptide that contains the amino acids Ala, Arg, Glu, Gly, Leu, Phe,…

A: The Edman degradation of heptapeptide cleaves amino acid Leu and carboxypeptidase form amino acid…

Q: Reaction of a polypeptide with carboxypeptidase A releases Met. The polypeptide undergoes partial…

A:

Q: Show how solid-phase peptide synthesis would be used to make Ile-gly-asn

A: The first step of solid-phase peptide synthesis to make ile-Gly-Asn is shown below.

Q: Bradykinin is a linear nonapeptide released by blood plasma globulin in response to a wasp sting.…

A: The peptide contains 9 amino acids.

Q: Which of the following is an acceptable name for the peptide sequence below?

A: While naming the amino acid sequence, start from N-terminal and end on C-terminal, so, it will be…

Q: Outline the steps needed to synthesize the tetrapeptide Ala–Leu–Ile–Gly using the Merrifield…

A: In the first step of synthesis, amino group of Gly is protected by 9-fluorenylmethyl chloroformate,…

Q: A nonapeptide released by globulins in the blood in response to a wasp sting. Hydrolysis gives the…

A: Given: We have to prepare nanopeptide.

Q: Suggest a scheme you will follow to synthesize the dipeptide Ala-Gly

A:

Q: An octapeptide contains the following amino acids: Arg, Glu, His, Ile, Leu, Phe, Tyr, and Val.…

A:

Q: Answer only In base solution, an amino acid is in acid solution, an amino acid is and exists…

A: Amino acids are compounds which contain both an amino group and an acidic group. Alpha amino acids…

Q: In a paragraph form, provide the experimental procedures in the chemical synthesis of protein that…

A: Experimental procedures in the chemical synthesis of protein that contain native serine residues by…

Q: Show how solid-phase peptide synthesis would be used to make Ile-Gly-Asn.2

A: The first step of solid-phase peptide synthesis to make ile-Gly-Asn is shown below.

Q: An unknown decapeptide was isolated and characterized. Complete hydrolysis of this peptide gave :…

A: Carboxypeptidase hydrolyzes the peptide bond present at the C-terminal position, so amino acid A…

Q: In a paragraph form provide the experimental procedure of the reaction of oxazetidine-containing…

A: Proteins are composed of amino acids in which amine group of one amino acid linked to carboxyl group…

Q: A sample of an unknown peptide was divided into two aliquots. One aliquot was treated with trypsin;…

A: To get the sequence of original peptide, we arrange the given fragments one above another according…

Q: Why is the amino acid proline not commonly found in alpha-helices or beta-sheets?  In what secondary…

A: The reason for proline not found in α helix or β sheet:It can’t donate an amide hydrogen bond.The…

Q: α-Amino acids can be prepared by treating an aldehyde with ammonia/trace acid, followed by hydrogen…

A: Strecker synthesis is a method of synthesize α-amino acids by treating an aldehyde with…

Q: shows the specificity pockets. The S₁ pocket has a glutamic acid in the bottom, the S₂ pocket is…

A:

Q: A tetradecapeptide (14 amino acid residues) gives the following peptide fragments on partial…

A: Phe-Val-Asn-Gln-His, His-Leu-Cys-Gly-Ser, Gly-Ser-His-Leu-Val. The tetrapeeptide fragments formed on…

Q: A decapeptide has the following amino acid composition: Ala2 , Arg, Cys, Glu, Gly, Leu, Lys, Phe,…

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: Match the products with the relative amounts that would be formed from complete hydrolysis of the…

A:

Q: Determine the primary structure of an octapeptide from the following data: Acid-catalyzed hydrolysis…

A: The acid-catalyzed hydrolysis gives the list of all amino acids present in the given polypeptide.…

Q: For the following hexapeptide shown below, answer the following questions. E-N-D-Y-K-L Draw the…

A: Hexapeptide given is: E-N-D-Y-K-L

Q: A decapeptide has the following amino acid composition. Ala2, Arg, Cys, Glu, Gly, Leu, Lys, Phe, Val…

A:

Q: Suppose you are trying to synthesize the dipeptide Val-Ser. Compare the product that would be…

A: Thionyl chloride is used to convert the carboxylic acid into acid chloride.

Q: Serine esterase contains a catalytic triad at its active site. Which amino acid in serine esterase…

A:

Q: Draw a structure for a peptide that gives Gly, Ile & Phe on hydrolysis and fails to react with…

A: Amino acids are the building blocks of proteins. Peptides are formed by the combination of two or…

Q: What is the structure of below amino acid at its isoelectric point: (a) alanine;

A: Amino acid consists a central carbon atom which is attached to an amine group, (-NH2) and a…

Q: A decapeptide has the following amino acid composition: Ala2 , Arg, Cys, Glu, Gly, Leu, Lys, Phe,…

A: The tripeptide has lysine as N-terminal. Now writing all these tripeptide in such a manner that…

Q: Three peptides were obtained from a trypsin digestion of two different polypeptides. indicate the…

A:

Q: A tetrapeptide is given as: Ser-Lys-Ala-Phe. Which statement is true? a. The listing should be in…

A:

Q: His-Met-Asp-Tyr-Phe-Ser within this peptide, which amino acid residue is the most hydrophobic and…

A: Hydrophobic amino acids are those with side-chains that do not like to reside in an aqueous…

Q: Vancomycin is made up of a peptide chain consisting of seven amino acids and there are 3 phenyl…

A:

Q: Show the peptides that would result from cleavage by the indicated reagent:…

A: Carboxypeptidase A is a type of exopeptidase.This indicates that it is responsible for hydrolysis of…

Q: Suggest a reasonable strategy for the synthesis of the dipeptide Leu-Phe, using established protocol…

A: The biomolecules which have carboxylic and amine group containing monomer units are known as…