Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
Bartleby Related Questions Icon

Related questions

bartleby

Concept explainers

Question
4
Decytospolides A and Bare fungal natural products that are toxic to some cancer cells, In a synthesis of these natural products.
compound 3 was prepared via the reaction between an epoxide (compound 2) and a Grignard reagent (Tetrahedron: Asymmetry 2015.
26, 296-303). Draw the structure of 2, and provide a complete mechanism for the conversion of 1 to 3.
OBn
OBn
NaH
TeO
2) H0
Bn
Decytonpolide A R-H)
Decytospolide R- COCH)
13.25 a
13,25 d
Incorrect.
Add curved arrow(s) to draw step 1 of the mechanism for the conversion of compound 2 to compound 3 (note that the Grignard
reagent is represented as a carbanion). Modify the given drawing of the product as needed to show the intermediate that is
formed in this step.
Edit Drawing
Hint
expand button
Transcribed Image Text:Decytospolides A and Bare fungal natural products that are toxic to some cancer cells, In a synthesis of these natural products. compound 3 was prepared via the reaction between an epoxide (compound 2) and a Grignard reagent (Tetrahedron: Asymmetry 2015. 26, 296-303). Draw the structure of 2, and provide a complete mechanism for the conversion of 1 to 3. OBn OBn NaH TeO 2) H0 Bn Decytonpolide A R-H) Decytospolide R- COCH) 13.25 a 13,25 d Incorrect. Add curved arrow(s) to draw step 1 of the mechanism for the conversion of compound 2 to compound 3 (note that the Grignard reagent is represented as a carbanion). Modify the given drawing of the product as needed to show the intermediate that is formed in this step. Edit Drawing Hint
Expert Solution
Check Mark
Knowledge Booster
Background pattern image
Chemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Text book image
Chemistry
Chemistry
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning
Text book image
Chemistry
Chemistry
ISBN:9781259911156
Author:Raymond Chang Dr., Jason Overby Professor
Publisher:McGraw-Hill Education
Text book image
Principles of Instrumental Analysis
Chemistry
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Cengage Learning
Text book image
Organic Chemistry
Chemistry
ISBN:9780078021558
Author:Janice Gorzynski Smith Dr.
Publisher:McGraw-Hill Education
Text book image
Chemistry: Principles and Reactions
Chemistry
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:Cengage Learning
Text book image
Elementary Principles of Chemical Processes, Bind...
Chemistry
ISBN:9781118431221
Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:WILEY