Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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co
S
Question #6. On the right is a schematic showing the structure of complex V
(ATP Synthase). The various subunits are labeled.
6A Label the figure to show the location of the mitochondrial matrix
αβλαβ
Y
6B On the figure indicate the direction of proton flow across the membrane in
the direction of ATP synthesis. Make sure to specifically indicate through which
portion of the complex the protons move.
E
Ab, a
a cc ccc
Inner membrane
6C List the specific subunits in the complex that rotate as protons flow through
the complex (select from: a, b2, c, a, ß, y, 8, ɛ)
6D Rotation occurs in 120° steps. Briefly explain why this is consistent with the
bind-and-change mechanism that produces ATP. In your answer, make sure to indicate the number of active sites in the
complex and how rotation alters their ability to promote catalysis.
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Transcribed Image Text:co S Question #6. On the right is a schematic showing the structure of complex V (ATP Synthase). The various subunits are labeled. 6A Label the figure to show the location of the mitochondrial matrix αβλαβ Y 6B On the figure indicate the direction of proton flow across the membrane in the direction of ATP synthesis. Make sure to specifically indicate through which portion of the complex the protons move. E Ab, a a cc ccc Inner membrane 6C List the specific subunits in the complex that rotate as protons flow through the complex (select from: a, b2, c, a, ß, y, 8, ɛ) 6D Rotation occurs in 120° steps. Briefly explain why this is consistent with the bind-and-change mechanism that produces ATP. In your answer, make sure to indicate the number of active sites in the complex and how rotation alters their ability to promote catalysis.
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