Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question 17 ( Here is a step from the citric acid cycle enzyme citrate synthase. His274 s-COA H- s-COA Asp375 Substrate is black and enzyme residues are green. What are the roles of His274 and Asp375 respectively? (Order is important.) O Positioning substrate and transition state and an acid A base and a base O An electrophile and a base An acid and a base Positioning substrate and transition state and a base. An electrophile and an acid
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Transcribed Image Text:Question 17 ( Here is a step from the citric acid cycle enzyme citrate synthase. His274 s-COA H- s-COA Asp375 Substrate is black and enzyme residues are green. What are the roles of His274 and Asp375 respectively? (Order is important.) O Positioning substrate and transition state and an acid A base and a base O An electrophile and a base An acid and a base Positioning substrate and transition state and a base. An electrophile and an acid
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