Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Describe cell cycle and the role cyclin-cdk complexes play in the cell cycle.
-Write out what each phase is and how it is regulated.
-Describe the importance of each part and its checkpoints.
-Describe the three major cell cycle checkpoints
i) List each checkpoint
ii) Link that checkpoint to a type of DNA damage
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- Explain and give the importance of cell cycle checkpoints in the different phase of the cell cycle.arrow_forwardDescribe the roles of HER2, MAP kinase (ERK), Akt, cyclin D1, and p27 in regulating cell proliferation and survivalarrow_forwardDuring the cell cycle there are three checkpoints. Match each description with the correct checkpoint. Requires growth signals and checks there are no mutation in the DNA Checks that DNA is properly replicated and that all the organelles and proteins needed for division are present Ensures that all the chromosomes are lined up and accounted for A. G1/S B. S/G2 C. G2/M D. Metaphase/Anaphase E. Anaphase/Telophasearrow_forward
- What celluar events/processes are associated with G1,S,G2,and M phases of the cell cycle? With the phases of mitosis? Some example: A. DNA replication B. Beginning of mitosis C. Normal cell growth and function D. Breaksdown of nuclear membrane E.Separation of sister chromatids F.Alignment of chromosomes on the equator of the cell H.Triggering the compaction and condensation of chromosomes I. Attachment of microtubles to kinetochoresarrow_forwardDO NOT COPY IN GOOGLE OR BARTLEBY QUESTIONS: -What is meant by a cell cycle checkpoint? -What is its importance? -How does a cell stop it's progress at one of these checkpoints?arrow_forwardWhich of the following need to be expressed to get past the G1 checkpoint and why? Select one: a. All the answers are correct and needed to progress the cell past the G1 checkpoint by expressing the enzymes necessary for DNA replication. Once these proteins are all expressed, the cell has moved past G1 into S phase. b. Primase because this enzyme is needed for DNA replication moving the cell from G1 to S. c. Cyclins because the accumulation of specific cyclins will turn on CDKs needed to turn on gene expression for proteins involved in DNA replication, moving the cell from G1 to S. d. DNA helicase because this protein is needed for DNA replication (part of S phase). So expression will help progress the cell from G1 to S.arrow_forward
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