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Please answer fast
Create a concept map linking hemoglobinopathies to the molecular foundations of these diseases and disorders for Sickle Cell Anemia.
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- What recent advancements in hematology research have shed light on the role of non-coding RNA molecules in regulating hematopoiesis and hematological disorders?Discuss the morphological classification of anaemia and explain why it is Important.List 3 differences between sickle cell and b-thalassemia
- give the Molecular basis of each disease given below. 1 Cystic fibrosis 2 Sickle cell anemia 3 Marfan syndrome 4 Thalassemias 5 HemochromatosisDifference between heomophilla and sickle-cell anemia?BACKGROUND A 2-year-old black girl is being seen by the hematologist after her pediatrician found her to be severely anemic with splenomegaly and jaundice. Her mother gives a possible history of a “blood problem” in her family but doesn’t know for sure. Her hemoglobin electrophoresis was normal, and the complete blood count (CBC) revealed a normocytic anemia. The platelet and white blood cell counts are normal. On the peripheral smear, there are many bizarre erythrocytes, including spiculated cells. A diagnosis of pyruvate kinase deficiency is made. Pyruvate kinase deficiency (PKD) can be inherited in an autosomal recessive manner, which means that a child must inherit a gene with the disease-causing mutation from both parents in order for the disorder to be inherited. The PLKR gene regulates the synthesis of the pyruvate kinase enzyme, which is located in the liver and red blood cells. Pyruvate kinase deficiency (PKD) is a rare genetic disorder characterized by the premature…
- At the end of the day, Rina is already feverish, with dry cough and a throat that really hurts when she swallows. Succeeding days revealed that the doctor and assistant's condition did not get better. Both were brought to the hospital by their respective families and COVID test were done to them. Please answer the following and limit answers to one sentence for each. 1. What is a carrier? 2. Describe the following: a. asymptomatic carrier b. symptomatic carrier c. incubatory carrier d. convalescent carrier e. chronic carrierCan you postulate a reason or reasons why children with Down syndrome are 20 times more likely to develop leukemia than children in the general population?Explain the terms: colorblindness, Haemophilia & Sickle-cell anaemia.
- What the linked video below and answer the questions below https://youtu.be/z3k3GZ1F_rg 1) What causes sickle cell crisis?Which of the following is FALSE regarding sickle cell anemia? O it is an advantage to be a heterozygote for sickle cell anemia in areas where malaria is prevalent heterozygotes for sickle cell anemia can still have aggregation/polymerization of hemoglobin under conditions of low oxygen O individuals that are sickle cell anemia homozygotes are disadvantaged because they are more susceptible to malaria O the advantage to being a heterozygote for sickle cell anemia disappears when malaria is not an issuePLEASE ANSWER BRIEFLY. Thank you. 1. Differentiate the acute leukemias from the chronic leukemias as to: a. maturational stage of cells that predominate in blood / bone marrow. b. chronologic type( life expectancy after diagnosis) 2. Contrast the bases of FAB classification of leukemias from the bases of WHO classification.
