Consider the ventricular cardiomyocyte action potential shown below: a) Which phase of the cardiac myocyte action potential would be most significantly affected by the L-type calcium channel blocker nifedipine? b) Draw the predicted effects of nifedipine on the cardiac myocyte action potential.
Consider the ventricular cardiomyocyte action potential shown below: a) Which phase of the cardiac myocyte action potential would be most significantly affected by the L-type calcium channel blocker nifedipine? b) Draw the predicted effects of nifedipine on the cardiac myocyte action potential.
Anatomy & Physiology
1st Edition
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Chapter12: The Nervous System And Nervous Tissue
Section: Chapter Questions
Problem 40CTQ: What does it mean for an action potential to be an all or none event?
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Consider the ventricular cardiomyocyte action potential shown below:
a) Which phase of the cardiac myocyte action potential would be most significantly affected by the L-type calcium channel blocker nifedipine?
b) Draw the predicted effects of nifedipine on the cardiac myocyte action potential.
Transcribed Image Text:50
-100
time
membrane potential (mV)
50
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