Consider the following reaction sequence for the synthesis of Ibuprofen: CO₂Et 1) NaOEt A 2) (EtO)₂C=O 1) NaOEt 2) CH3l B H3O+ Δ .CO,H Ibuprofen 2.1 Propose a reaction mechanism for the formation of intermediate A. 2.2 Propose a reaction mechanism for the formation of intermediate B.

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Chapter1: Chemical Foundations
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Consider the following reaction sequence for the synthesis of Ibuprofen:
CO₂Et
1) NaOEt
A
2) (EtO)₂C=O
1) NaOEt
2) CH3l
B
H3O+
Δ
.CO,H
Ibuprofen
2.1 Propose a reaction mechanism for the formation of intermediate A.
2.2 Propose a reaction mechanism for the formation of intermediate B.
Transcribed Image Text:Consider the following reaction sequence for the synthesis of Ibuprofen: CO₂Et 1) NaOEt A 2) (EtO)₂C=O 1) NaOEt 2) CH3l B H3O+ Δ .CO,H Ibuprofen 2.1 Propose a reaction mechanism for the formation of intermediate A. 2.2 Propose a reaction mechanism for the formation of intermediate B.
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