
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
Make an experimental procedure for the synthesis of ascorbic acid from glucose:

Transcribed Image Text:HU
HO
L- Ascorbic
Acid
HQ
D-Glucose
HO
OH
HO
OH
6) HCI, PhMe
Spontaneous
H2,
Ranitidine
Enayme 1
OH
HO
OH
HO
2- keto - qulono-
HO
D-Gluconic
Acid
gamma-
lactone
HO
OH
OH
4. NaOCI, NICI
5. Hz0, H+
A cetobacter
supphxagns
(pH4- 30-35°C)
Gulo enzyme Cinactive
in humans } primates)
Enzyme 2
OH
но
HO
D- Gluconic
Acid Lactane
L- Gulono Lactone
HO
HO
Enzyme 3
Acetone , Sulfuric Acid
Но
HO
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