Answered: CHALLENGE PROBLEM: The phosphates that…

CHALLENGE PROBLEM: The phosphates that make up the phosphodiester bonds in DNA have pka 2. When the pH of solution is dropped to 2.5, what is the DNA which is 97.000-

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter28: Nucleic Acids

Section: Chapter Questions

Problem 28.37P

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Glucogenesis is a metabolic pathway in which glucose is produced from carbon substrates that are not carbohydrates. This process is observed in plants, animals, fungi, bacteria and other micro organisms. The general definition for glucogenesis or gluconeogenesis is as follows,

Question

Please don't provide handwriting solution

CHALLENGE PROBLEM: The phosphates
that make up the phosphodiester bonds in
DNA have pka ≈ 2. When the pH of
solution is dropped to 2.5, what is the
charge of C. elegans DNA, which is 97,000-
kilo-base-pairs (kbp) long?

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Step 1: Introduction

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Step 2: DNA Structure

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Step 3: Phosphodiester bonds and pKa

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Step 4: DNA is 97,000 kilobase pairs

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