Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Cancer cells treated with vitamin E succinate are generally more vulnerable to rupture of their lysosomal membranes (and subsequent apoptosis) than are normal cells, because:
- cancer cells often have an acidic cytosol, and their lysosomes have an acidic pH too
- cancer cells often have an acidic cytosol, but their lysosomes have an alkaline pH
- cancer cells often have an alkaline cytosol, and their lysosomes have an alkaline pH too
- cancer cells often have an alkaline cytosol, but their lysosomes have an acidic pH
- all of the above
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- Why is assembly of microtubules so much more efficient inside cells than in a test tube? The centrosome functions to nucleate assembly of microtubules in the cell, which is only found in the cell. The concentration of tubulin subunits is always higher in a cell than can be achieved in a test tube. Microtubule assembly requires ATP, which is only found in the cell. Microtubule assembly requires Tau, which is only found in the cell.arrow_forwardThe function of FtsZ was determined in part by using a temperature-sensitive ftsZ mutant. What is the phenotype of an ftsZ mutant when it is grown at 37°C? Cells of random sizes (some very small) are formed after cell division Normal sized cells are formed after cell division Cells do not divide, and turn into long filaments Cells die immediately upon shifting to 42°Carrow_forward1-what are the largest element of the cytoskeleton and can dynamically grow and shrink by the addition or subtraction of tubulin subunits. 2-Many less dynamic, more permanent cellular structures such as the nuclear lamina have (????) as the major cytoskeletal component Microtubules Intermediate filaments Microfilaments 3-when a ligand binds a (????) the conformation of the receptor changes, opening a selective pore. GPCR Ligand gated ion channel Ligandase pore Voltage gated ion channelarrow_forward
- The following figure shows the 3D structure of a tubulin dimer. A mutation in the beta tubulin subunit (shown in red) prevents the binding of a GTP molecule. Predict the consequences that this mutation will have on the microtubule and on cell division. Please be specific. Alpha tubulin Beta tubulinarrow_forwardSome antimicrobial drugs used to treat bacterial infections disrupt the process of protein synthesis. What could these drugs target? Why would this ultimately lead to cell death?arrow_forwarddescribe the process of lysosomal hydrolase arriving to the lysosome. without including translationarrow_forward
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