
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Question
Disorder 2 is associated with the.....
chose one
1. mitochondria
2. lysosome
3. ribosome
4. endoplasmic reticulum

Transcribed Image Text:Described below are a collection of five human diseases/disorders, each associated in some
way with a cellular organelle. Based on these descriptions and your knowledge of the structure
and function of cellular organelles, identify the organelle that is associated with each disorder.

Transcribed Image Text:Disorder 2:
Some people are born with or acquire a gene mutation that causes a certain defective organelle
to be produced. A quality control system in cells eliminates most of the faulty organelle, but
this leaves few available for cells to use to produce required proteins, which causes anemia and
bone marrow failure early in life. Next, a second gene mutation suppresses the quality control
system, making more defective copies of this organelle available to cells. This results in changes
in gene expression patterns that can result in cancer.
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