Ca2+ Phosph

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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What membrane transport family is this protein part of? What are the roles of the different domains of this protein?

Transmembrane (M) domain
Lumen
Cytosol
Ca2+
Actuator (A)
domain
Phosphorylation (P)
domain
Nucleotide-
binding (N)
domain
Phosphorylation'
site
ATP-binding site'
Transcribed Image Text:Transmembrane (M) domain Lumen Cytosol Ca2+ Actuator (A) domain Phosphorylation (P) domain Nucleotide- binding (N) domain Phosphorylation' site ATP-binding site'
Expert Solution
Step 1

The endoplasmic reticulum ( ER) is an important organelle which serves as an intracellular calcium ( Ca2 +) store that can be released into the cytoplasm quickly to cause a variety of cellular responses. To reach the cell surface, transmembrane proteins must pass through the secretory pathway, where they can communicate with other cells and respond to signalling signals.

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