Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Briefly discuss how sickle cell mutation affects the protein.
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- 1st answer choices: yes, no 2: yes, no 3:increase, decrease 4: a lot of mRNA or very little mRNA 5: less mRNA, more mRNA, or the same amount of mRNAarrow_forwardExplain the following diagram. It refers to a pedigree on the disease called phenylketonuria. Briefly explain about the disease; specifically biochemical and genetic aspects. Then I interpret the pedigree. Say what type of inheritance the condition exhibitsarrow_forwardhow do i expand this into 1000 words The methodology employed to identify differentially expressed genes (DEGs) in breast cancer using RNA-Seq data involves several systematic steps integrating data retrieval, analysis, normalization, DEG identification, and functional annotation. Initially, raw RNA-Seq data is retrieved from the NCBI GEO database, specifically from dataset GSE216238 (Nakshatri, 2023), which encompasses samples from both breast cancer and normal tissue. Subsequently, the raw data was imported into Excel for initial analysis, leveraging its widespread availability and user-friendly interface. Gene expression data for breast cancer analysis was obtained from the Gene Expression Omnibus (GEO) database. The GEO homepage (https://www.ncbi.nlm.nih.gov/geo/) was accessed, and the "Query & Browse" tab was selected. Advanced Search: Under "Search GEO DataSets," an advanced search was conducted (https://www.ncbi.nlm.nih.gov/gds/advanced). Keywords "breast" and "cancer" were…arrow_forward
- See photo attached.arrow_forwardEdugence - dugence.com/student/studentformative/ Online Tools Juan Bonilla Velasquez > Nimitz 20-21: CA Biology Pros G. Question 14 (2014 6E) Sickle-shaped red blood cells result from a mutation in the gene that codes for hemoglobin. This mutation results in sickle-cell anemia. A partial sequence of bases from a normal hemoglobin gene and a sequence that results in sickle-cell anemia are shown below. Normal hemoglobin: T-G-A-G-G-T-C-T-C-C-T-C Sickle-cell hemoglobin: T-G-A-G-G-T-C-A-C-C-T-C What type of mutation is depicted in the sequence? Answer Substitution G Insertion Deletion J Frameshift Question 14 Next Previors Kach B Technoloes inc2021 Edugence Sign outarrow_forwardPlease Write a Brief Note on "Treatment for the genetic disorders by using gene therapy " Please write at your own words, please...arrow_forward
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