Bicarbonate/carbonic acid buffer in blood is an example of an equilibrium reaction that is meant to be very insensitive to change. How does the bicarbonate/carbonic acid buffer re-establish equilibrium if acidity increases? How does the bicarbonate/carbonic acid buffer re-establish equilibrium if alkalinity increases?
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- Bicarbonate/carbonic acid buffer in blood is an example of an equilibrium reaction that is meant to be very insensitive to change. How does the bicarbonate/carbonic acid buffer re-establish equilibrium if acidity increases? How does the bicarbonate/carbonic acid buffer re-establish equilibrium if alkalinity increases?
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- Consider the equilibrium shown below; indicating the buffering system in the blood circulation. CO, + H,0 [H,CO3] HCO3¯+H* When a patient is choking, would this lead to an alkalosis or an acidosis situation? Explain.Buffer systems can absorb hydrogen ions from the blood to increase pH into homeostatic range (pH: 7.35 to 7.45)During what condition would buffer systems do this?Calcium carbonate (CaCO₃(s)) is an important building material (limestone) and a quick cure for acid indigestion (TUMS). Ksp = 8.7x10⁻⁹ for CaCO₃(s). What, if any, is the effect of lowering the pH (as occurs in acid rain and acid indigestion) on the solubility of CaCO₃(s). (hint: use Le Chatelier's principle) A) there is no effect from lowering pH on CaCO₃(s) solubility B) lowering pH increases the CaCO₃(s) solubility C) additional information is required to determine the outcome D) lowering the pH lowers the solubility
- Metabolic alkalosis refers to a process whereupon decreased hydrogen ion, or increased bicarbonate, concentrations occur in the body, and the blood pH becomes too basic. Answer the following questions: How does the body regain its acid-base equilibria/balance? What happens when that balance does not happen? Will a buffer system still work under these conditions?Three systems of the body help regulate acid/base balance - buffer system, respiratory system and renal system. Describe the renal response in a person experiencing metabolic alkalosis due to severe vomiting. Provide the general formula for pH control in acid/base regulation.define buffer and write chemical equations for thebicarbonate, phosphate, and protein buffer systems;
- During the treatment for COVID-19, one complication includes an increase of CO2 in the lungs. This buildup of CO2 can result in a serious condition called respiratory acidosis if the level of H+ significantly changes. If the pH drops by 1 unit, what has happened to the H+ concentration?The glass electrode used in commercial pH meters gives an electrical response proportional to the concentration of hydrogen ion. To convert these responses to a pH reading, the electrode must be calibrated against standard solutions of known H+ concentration. Determine the weight in grams of sodium dihydrogen phosphate (NaH2PO4 · H2O; FW 138) and disodium hydrogen phosphate (Na2HPO4 ; FW 142) needed to prepare 1 L of a standard buffer at pH 7.00 with a total phosphate concentration of 0.100 M . See Problem 24 for the pKa values of phosphoric acid.Write a net ionic equation that shows how this buffer neutralizes added acid (HCl).
- A 2-year-old child presents with metabolic acidosis after ingesting an unknown number of flavored aspirin tablets. At presentation, her blood pH was 7.0. Given that the pKa of aspirin (salicylic acid) is 3, calculate the ratio of its ionized to un-ionized forms at pH 7.0.Normal arterial pH is 7.35 to 7. 45. Both metabolic and respiratory alkalosis have pH more basic compare to the normal arterial pH. The difference is 0.5 units. What is pH value in alkalosis? Niemann-Pick type C disease is a progressive neurological disease; symptoms include unsteady walking with uncoordinated limb movements, slurred speech, a difficulty in swallowing, epilepsy and tremor. This condition is due to the abnormal functioning of a lysosome. State the normal functions performed by this organelle.Explain thoroughly the Buffering Action of following Biological or Physiological Buffers:(a) Phosphate Buffer System.(b) Bicarbonate Buffer system.