BAX proteins stimulate apoptosis. Mutations in BAX genes can help developing cancers but not necessarily trigger a tumor. This is because

Q: Oncogenes show a of mutation, while tumor suppressor genes show a of mutations. is the process by…

A: Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread…

Q: The p53 gene was discovered in 1979, but it was not clear whether the gene functioned as an oncogene…

A: An oncogene is a type of gene that is responsible for causing the cells to divide uncontrollably and…

Q: Explain how p53 functions as a tumor suppressor gene. How can mutations in p53 lead to cancer, and…

A: Normal cell has low level of p53 protein. When DNA damage or other stress signals may trigger p53…

Q: Occurred in her cells? (Unfortunately her parents have passed away.) I think these genes are…

A: CRISPR stands for Clustered regularly interspaced short palindromic repeats. It is a system of…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Medical technology has advanced significantly over the course of many centuries. According to…

Q: Discuss the complete cell cycle in a human cell, mitosis and meiosis, and the regulatory components…

A: There are two types of cell division.They are Mitosis and Meiosis. Most of the times,the type of…

Q: Characterize the differences between tumor cells and normal cells in terms of the following…

A: A. The normal cell shows contact inhibition that means when two cells get contact then the growth…

Q: A scientist notices that a cancer cell line fails to die when he adds an inducer of apoptosis to his…

A: Apoptosis is the programmed cell death. It occurs as a cell response to various signalling pathways,…

Q: Describe in detail the relevance of apoptosis to cancer therapy

A: Apoptosis or programmed cell death  It is a highly regulated process that allows a cell to self…

Q: Explain why mutations in tumor suppressor genes are recessive (both copies of the gene must be…

A: Mutation in an organism is defined as a permanent alteration of “nucleotide sequences”. The…

Q: Part A and B A. What is the normal function of the Rb protein? A) Rb prevents the cell cycle from…

A: Answer A) Rb is Retinoblastoma protein which is a tumor suppressor protein and belongs to pocket…

Q: The normal function of one tumor-suppressor gene acting at the G1 checkpoint is to prevent cells…

A: The cell cycle consists of four steps- G1, S, G2, and M phases. In the G1 phase, the cell increases…

Q: Describe the molecular mechanisms involved in P53’s role as a tumor repressor protein.

A: The TP53 gene provides instructions for making a protein called tumor protein p53 (or p53). This…

Q: Although tobacco smoking is responsible for a large number of human cancers, not all smokers develop…

A: Cancer refers to the uncontrolled cell division caused by the mutations in the genes which control…

Q: Which of the following is not a tumor suppressor gene? a.RET b.RB c.BRCA1 d.BRCA2

A: A normal cell undergoes regulated division, differentiation, and apoptosis (programmed cell death).…

Q: Tissues and differentiation: a) Explain what is meant by determination and differentiation b)…

A: In biology, the process of determination is related to the process in which embryonic stem cells…

Q: Cancer is caused by many different types of gene mutations. Some mutations are in proto-oncogenes,…

A: Cells split into new cells so that the body uses them and cancer starts with this wonderful…

Q: Describe, using specific examples, the differences in how a growth factor gene and a tumor…

A: When we talk about cancer, there are certain genes associated with it. Oncogenes are genes that are…

Q: A research study indicated that an agent in cigarette smoke caused the silencing of a tumor…

A: The TP53 gene provides instructions for making a protein called tumor protein p53 (p53). This…

Q: Normal (nonmutant) tumor-suppressor genes often functiona. as negative regulators of cell…

A: Cancer is defined as the biological disorder in which the cells undergo uncontrolled growth and cell…

Q: Cancer often results from a multistage process involving an initiating event (mediated by a viral…

A: Phorbol esters are a group of chemicals that are found in many plants. They are the ester…

Q: Much remains unknown about the rapid, uncontrolled growth, or what causes a tumor to metastasize.…

A: Cancer is a disease in which abnormal cells divide uncontrollably and destroy body tissue. A…

Q: Which of the following statements about cancer is false? (a) oncogenes arise from mutations in…

A: Proto Oncogenes are the genes that cause cancer when there are alterations in them. Several factors…

Q: BRCA1 is a gene that codes for a tumor suppressor protein.  If a person inherits a mutation in…

A: A mutation is a change in the nucleotide sequence. Certain mutations does not cause a change in the…

Q: Explain the difference between proto-oncogene and tumor suppressor mutations in terms of its…

A: Cancer is a medical condition that is characterized by the growth of tumors in the body of an…

Q: BAX proteins stimulate apoptosis.

A: A natural genetically programmed cell death called apoptosis occurs when an ageing cell reaches the…

Q: Cells in a tumor contain mutated copies of a particular gene that promotes tumor growth. Gene…

A: An oncogene helps in control cell division and  contributes to cancer progression whereas a tumor…

Q: is a normal cellular gene that through a A an oncogene. OA) proto-oncogene...loss-of-function OB)…

A: An oncogene is a cancer-causing gene that has been mutated. A proto-oncogene is a type of oncogene…

Q: mutation in p53 promoter that prevents p53 from being expresses Causes? Why? A. Increased…

A: Cancer is a condition in the body where cells in particular tissues lose the function of apoptosis…

Q: Part A. Gene Q's normal function is to cause apoptosis (cell death) for cells that have chromosome…

A: Cancer in simple term can be referred to a set of diseases which are caused by the production of an…

Q: A tumor suppressor gene (TSG) codes for a protein that is part of the system that regulates cell…

A: Normal genes that halt cell division or fix DNA errors are known as tumor suppressor genes. Such…

Q: Apart from p53, mention and describe the function of three tumor suppressor genes you know

A: The cancer related genes can be divided into two broad categories like the proto-oncogenes and tumor…

Q: Which of the following statements correctly describes a characteristic of tumor-suppressor gene? a)…

A: Cells that progress through the cell cycle unchecked may sequentially develop malignant tumors.…

Q: A cell inherits a mutation in a gene that results in a transcription factor, called NF-kB,…

A: Introduction :- Mutations are defined as the changes in the DNA sequence and thus , hereditary in…

Q: Tissues and differentiation a)Explain what is meant by termination and differentiation ).b) Explain…

A: The question has been assumed to be "a)Explain what is meant by determination and…

Q: Part A and B A. What are the Hallmarks of Cancer? A) Criteria that are used to identify tumors in…

A: The hallmarks of cancer are the biological capabilities that are required during the development of…

Q: Which could lead to uncontrolled growth in cancer?   A. A nonfunctional E2F protein     B. The…

A: a)A nonfunctional E2F protein: False E2F is a transcription factor that is the principal target of…

Q: P53 is a tumor suppressor protein.   The protein is present in the cell at all times but is…

A: Given information: P53 is a tumor suppressor protein.   The protein is present in the cell at all…

Q: a. How could you use sequence analysis to determine if this patient inherited the mutation from one…

A: There are various diagnostic technique used to diagnose cancer and they are:- Biopsy, Breast MRI,…

Q: Proto-oncogenes normally function to increase v cell division. If a mutation occurs to a…

A: Proto - oncogenes normally function to stimulating cell division . If a mutation occurs to a proto -…

Q: A. What below would be likely to lead to cancer development? A) Overexpression of a cell cycle…

A: Overexpression of RTK (Receptor Tyrosine Kinase) leads to the increased local concentration of the…

Q: Cellular levels of tumor suppressor protein p53 is maintained by a ubiquitin ligase protein, called…

A: From the above information, we can make the following inferences - 1. p53, as indicated in the…

Q: With regard to cancer cells, which of the following statementsare true?A. Cancer cells are clonal,…

A: Cancer is a group of diseases involving abnormal growth of cells, which tend to proliferate in an…

Q: Describe how the tumor-suppressor genes Rb, p53 and p21 regulate the cell cycle.

A: Tumor suppressor gene  These gene controls the activity of cell division cycles. They decide whether…

Q: Some cancers have been treated with drugs that demethylate DNA.Explain how these drugs might work.…

A: Cancer is a disease that is associated with genetic changes. The mutations in the oncogenes and…

Q: Would a drug that induced apoptosis or one that induced necrosis be preferable for treatment of…

A: INTRODUCTION Flowcytometry Flowcytometry is a technique that simultaneously measures and analyse…