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Based on this data, which of the following is true of the cell lines? Select all that apply Cell line 3 will display a cancerous phenotype The important cell cycle control gene could be p16, whose gene product prevents progression through the cell cycle unless all checks out Cell line 3 will display a normal phenotype The important cell cycle control gene could be cyclin d, whose gene product drives G1 to S phase transition

Based on this data, which of the following is true of the cell lines? Select all that apply Cell line 3 will display a cancerous phenotype The important cell cycle control gene could be p16, whose gene product prevents progression through the cell cycle unless all checks out Cell line 3 will display a normal phenotype The important cell cycle control gene could be cyclin d, whose gene product drives G1 to S phase transition

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Your friend sends you two cancerous cell lines to examine and determine possible mutations. The results are shown below: Cell Line Mutation WT none (wild type DNA) 1 a deletion at the same region on both copies of chromosome 4 2 a point mutation in a gene on only one copy of chromosome 7 You learn that cell line 1 is a skin cancer cell line, and the deleted region normally contains an important cell cycle control gene. You obtain another cell line (cell line 3) that has one wild-type copy, and one loss-of-function mutant copy of this gene Based on this data, which of the following is true of the cell lines? Select all that apply Cell line 3 will display a cancerous phenotype The important cell cycle control gene could be p16, whose gene product prevents progression through the cell cycle unless all checks out Cell line 3 will display a normal phenotype V The important cell cycle control gene could be cyclin d, whose gene product drives G1 to S phase transition
Transcribed Image Text:Your friend sends you two cancerous cell lines to examine and determine possible mutations. The results are shown below: Cell Line Mutation WT none (wild type DNA) 1 a deletion at the same region on both copies of chromosome 4 2 a point mutation in a gene on only one copy of chromosome 7 You learn that cell line 1 is a skin cancer cell line, and the deleted region normally contains an important cell cycle control gene. You obtain another cell line (cell line 3) that has one wild-type copy, and one loss-of-function mutant copy of this gene Based on this data, which of the following is true of the cell lines? Select all that apply Cell line 3 will display a cancerous phenotype The important cell cycle control gene could be p16, whose gene product prevents progression through the cell cycle unless all checks out Cell line 3 will display a normal phenotype V The important cell cycle control gene could be cyclin d, whose gene product drives G1 to S phase transition
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