As a pharmacological researcher, you are tasked discover a drug for a neurodegenerative disease that caused by protein-misfolding. The protein- misfolding results in secretion of three or more enzymes with similar active sites but different allosteric sites. Those misfolded enzymes are wrecking havoc in the bodily functions. You understand the key to the cure of this disease is by disabling the misfolded enzymes. of enzyme Based on the knowledge of enzymatic activities, identify the type inhibitors that be used as a drug. Explain the mechanism of disabling the misfolded enzymes with the aids of a hand drawn diagram.

Q: Why does the specificity of the enzyme promote enzyme activity?

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Q: Allosteric Inhibitors are constructed of level of protein polypeptide chains (demonstrating. on each…

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Q: Enzyme inhibition (compare and contrast reversible and irreversible inhibitors)

A: Enzyme inhibition is the process by which rate of an enzyme catalyzed reaction is decreased.

Q: Define the term Inhibitition of Enzyme?

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Q: describe the mechanism of each class of inhibitor, including how they impact the effective…

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Q: Please help

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Q: How is protease a good example of a enzyme and what are its uses

A:

Q: The two types of enzyme activators are cofactors or coenzymes. True or false

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Q: Protein X can be phosphorylated. Why would the phosphorylated form of protein X elute AFTER the…

A: Note: Since you have posted multiple independent questions in the same request, we will solve the…

Q: nswer the following questions: 1.-What is an inhibitor and what is its role in enzyme activity?…

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A: Enzymes are biological catalysts that accelerate chemical reactions.

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Q: Consider the three-dimensional model of the tertiary structure of an enzyme below. Amino acids…

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Q: hich of the following are advantages of quaternary structure? Choose all correct nswers 1) The genes…

A: Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: What happens to the enzyme’s native conformation once it is denatured? What structural organization…

A: " Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: Why are irreversible enzyme inhibitors referred to as poisons?

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Q: Compare the KM and Vmax of the enzyme in the absence and presence of inhibitors to determine what…

A: Inhibitors are the molecules which decrease the efficiency of enzyme activity.

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Q: A biochemist is trying to determine the type of proteases they have isolated from walrus blubber.…

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Q: Consider the following statements: (1) All of the B vitamins are water-soluble. (2) The induced-fit…

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Q: Describe and explain the Examples of

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Q: T/F Both competitive and noncompetitive inhibitors bind reversibly to an enzyme (E), thereby…

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Q: Idris has successfully extracted enzymatic proteins from the fish viscera (intestines and stomach).…

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Q: What effect does the optimum pH and temperature have on enzyme function? Briefly explain with an…

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Q: Which of the following is the most probable catalytic triad of an enzyme that follows general acid…

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Q: what is the covalent modification doing to the enzyme

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Q: Discuss how enzyme, together with its cofactors/ coenzymes, interact with its substrate. How do…

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Q: Explain and discuss an advantage and a disadvantage of regulating enzyme activity via allosteric…

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Q: Describe the induced-fit model of enzyme activity.

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Q: The following statements are either True or False. Please label accordingly. a. L-Amino reductase is…

A: Since we only answer up to 3 sub-parts, we’ll answer the first 3. If you need help with other sub…

Q: Suggest a reason why heating a solution containing an enzyme markedly decreases its activity. Why is…

A: Enzymes are proteins. They are biocatalyst that increases the rate of a reaction. Enzymatic activity…

Q: Why must enzyme activity be monitored under standard conditions?

A: The enzyme is a biocatalyst where the enzyme attracts subtract for the binding to its active site…

Q: I. Indicate whether each of the following statements are true or false. 1. According to the…

A: Note: Since you have posted a question with multiple sub-parts, we will solve first three sub-parts…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.