The active (catalytic) site of an enzyme contains the side chains of amino acid residues that areconserved because they participate in the protein’s catalytic activity. The bulk of the enzyme,however, is not part of the active site. A substantial amount of energy is required to synthesizeenzymes. Why are these molecules so large?

The active (catalytic) site of an enzyme contains the side chains of amino acid residues that are
conserved because they participate in the protein’s catalytic activity. The bulk of the enzyme,
however, is not part of the active site. A substantial amount of energy is required to synthesize
enzymes. Why are these molecules so large?