APOE Allelic frequency Control EOAD LOAD Vascular disease e4 0.07 0.28 0.35 0.12 e3

Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Chapter13: Observing Patterns In Inherited Traits
Section: Chapter Questions
Problem 2DAA
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APOE Allelic frequency

Control

EOAD

LOAD

Vascular disease

e4

0.07

0.28

0.35

0.12

e3

0.88

0.70

0.63

0.87

  1. What group is used as a control here?
  2. Based on this data, do you think APOE e4 allele increases one’s chance to develop EOAD or LOAD? Defend your answer. Your answer has to refer to the specific data in the table.
  3. Suppose that you want to improve this case control study by controlling one more variable that is a known risk factor for Alzheimer’s disease, how will you design your groups? Specify the risk factor you want to control and how you plan to control it. 
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Evaluation refers to the process of examining and assessing the value, effectiveness, or success of an individual, program, project, policy, or system. It involves the systematic collection and analysis of information about the results and outcomes of an initiative in order to determine its strengths and weaknesses and to identify areas for improvement. Evaluation helps organizations to make informed decisions about how to allocate resources and implement changes in order to improve performance and achieve their goals. It can also provide a means of accountability and provide feedback to stakeholders. Evaluation can take various forms, including formative evaluation (to improve implementation), process evaluation (to assess implementation), and summative evaluation (to assess outcomes).

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