Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Altered chromosome structure can drastically affect an individual organism’s
A. reciprocal translocation, deletion, translocation
B. deletion, translocation, inversion
C. inversion, translocation, reciprocal translocation
D. translocation, inversion, duplication
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- The original gene order on the chromosome for eight linked genes is A B C D E F G H. What would the gene order be after an A through C duplication followed by a D through F inversion? a. A B C D E F G H b. A B C A B C D E F G H c. A B C A B C D F E G H I d. A B C A B F E D G H e. A B C A B C F E D G Harrow_forwardAn organism described as 2n=4 has the chromosomes below with genes indicated by letters and centromeres indicated by periods. Select the BEST description of the chromosome aberration present in this organism. HJM.NPQ HJM.NPQ S.TVXZ S.TVXXVZ Select one: 0 a. Paracentric Inversion O b. Reverse Tandem Duplication Oc. Robertsonian Translocation Od. Terminal Deletion e. Tandem Duplication Of. Nonreciprocal Translocation g. Interstitial Deletion Oh. Pericentric Inversion Homobrachial Displaced Duplication Oj. Heterobrachial Displaced Duplication Ok. Reciprocal Translocationarrow_forwardWhich of these changes in chromosome structure alter the total amount of genetic material?arrow_forward
- 1.Describe the rearrangement in chromosomes A-C. indicate the specific markers genes flanking the crossover/breakage points (e.g., a translocation with breakpoints between markers X and Z). 2.Chromosome rearrangements can be caused by crossing over between repetitive DNA sequences. Draw a picture similar to Figure showing how crossovers between repetitive sequences could have produced chromosome rearrangement A. indicate the location and orientation of the repetitive DNA segments relative to the marker genes.arrow_forwardPossible options: A. Autopolyploidy B. Allopolyploidy C. Chromosome duplication D. Pericentric inversionarrow_forward1) transposons are highly conserved DNA sequences that induce homologous recombination (true or false ) 2)Okazaki fragments are small pieces of RNA synthesized on the lagging strand during transcription (true or false) 3)homologous recombination is a eukaryotic chromatin exchange mechanism that is active during meiosis (true or false)arrow_forward
- Researchers have discovered that some regions of chromosomes are more likely than others to cross over, these areas of frequent crossing over are called "recombination hot spots". Gene A and B are 500,000 bp apart - the genes are either side of a recombination hot spot. Gene C and D are also 500,000 bp apart but the region containing genes C and D are not near a recombination hot spot. Would the map distance between A and B be the same as the map distance between C and D? Explain your answer.arrow_forwardThe following gene arrangements in a particular chromosome are found in different geographic regions. The changes in sequence were due to sequential inversions. ABCDEF DECAFB DEFACB AFEDCB Assuming that the arrangement in “a” is the original arrangement, in what sequence did the various inversion types arise?arrow_forwardIndicate which of the four major classes of rearrangements (deletion, duplication, inversions, and translocations) are most likely to be associated with each of the following phenomena. In each case, explain the effect. a. Semisterility b. Lethality c. Vulnerability to mutation d. Haploinsufficiency e. Hypermorphic mutation (a gain of function mutation that causes an increase in otherwise normal gene function) f. Crossover suppression g. Aneuploidyarrow_forward
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