Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Transcribed Image Text:Match the chromosomal rearragement shown below (a-d) with the term for that particular chromosomal rearrangement.
a.
A B
C
D
E
Original chromosome
A B
C D
E F
Rearranged chromosome
b.
A
B
C.
d.
A B
C
DE
F
G
A
M
N
C
D
3
E
S
A B
C
D G
A
B
C
D
Q R
G
M
N
P
EF
S
1. Duplication
2. Deletion
3. Translocation
4. Inversion
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- The original gene order on the chromosome for eight linked genes is A B C D E F G H. What would the gene order be after an A through C duplication followed by a D through F inversion? a. A B C D E F G H b. A B C A B C D E F G H c. A B C A B C D F E G H I d. A B C A B F E D G H e. A B C A B C F E D G Harrow_forwardAn organism described as 2n=4 has the chromosomes below with genes indicated by letters and centromeres indicated by periods. Select the BEST description of the chromosome aberration present in this organism. HJM.NPQ HJM.NPQ S.TVXZ S.TVXXVZ Select one: 0 a. Paracentric Inversion O b. Reverse Tandem Duplication Oc. Robertsonian Translocation Od. Terminal Deletion e. Tandem Duplication Of. Nonreciprocal Translocation g. Interstitial Deletion Oh. Pericentric Inversion Homobrachial Displaced Duplication Oj. Heterobrachial Displaced Duplication Ok. Reciprocal Translocationarrow_forwardA mechanism that may cause a translocation isa. the joining of reactive ends when two different chromosomesbreak.b. crossing over between nonhomologous chromosomes.c. crossing over between homologous chromosomes.d. either a or b.arrow_forward
- What is the mode of inheritance of the trait caused by the topoisomerase mutation? (You may wish to work out punnet squares to determine the correct mode.) B. B Topoisomerase 1 Defect 5 O X-linked Dominant O X-linked Recessive Autosomal Dominant Autosomal Recessive 1 7 11 8₂ 15 7 13 4 Boarrow_forward1.Describe the rearrangement in chromosomes A-C. indicate the specific markers genes flanking the crossover/breakage points (e.g., a translocation with breakpoints between markers X and Z). 2.Chromosome rearrangements can be caused by crossing over between repetitive DNA sequences. Draw a picture similar to Figure showing how crossovers between repetitive sequences could have produced chromosome rearrangement A. indicate the location and orientation of the repetitive DNA segments relative to the marker genes.arrow_forwardand down syndrome the victim has an extra chromosome 21. Therefore, down syndrome is a kind of ___ and results from ___. A. aneuploidy... nondisjunction of chromosome 21 during meiosis B. polyploidy... occurrence of meiosis without cytokinesis C. translocation… insertion of a transposon into chromosome 21 D. replication air… An extra cycle of DNA synthesis during the five phasearrow_forward
- Indicate which of the four major classes of rearrangements (deletion, duplication, inversions, and translocations) are most likely to be associated with each of the following phenomena. In each case, explain the effect. a. Semisterility b. Lethality c. Vulnerability to mutation d. Haploinsufficiency e. Hypermorphic mutation (a gain of function mutation that causes an increase in otherwise normal gene function) f. Crossover suppression g. Aneuploidyarrow_forwardWhich of the following does not apply to banding patterns in chromosomes a. are unique O b. are produced by stains O c. are helpful with karyotyping d. illustrate the same pattern with normal homologous chromosomes O e. All of the statements do apply to banding patterns on chromosomes. None of these statements are false.arrow_forwardChange in chromosome numbers will lead to abnormalities. Which of the following is a correct match between the chromosome number and the syndrome? A. Trisomy 18 : Patau syndrome B. Monosomy 18 : Turner syndrome C. XXXY : Klinefelter syndrome D. Trisomy 21 : Edward syndromearrow_forward
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