Answered: adrenaline adenylyl cyclase CYTOSOL GDP…

adrenaline adenylyl cyclase CYTOSOL GDP ATP dissociated R-subunit of PKA CAMP inactive PKA active РКА phosphorylase kinase glycogen phosphorylase GLYCOGEN G1P

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 14QP: If phenylalanine was not an essential amino acid, would diet therapy (the elimination of...

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Concept explainers

Cell Signaling

It allows cells to perform various cellular activities, coordinate, and interact with other cells. All cells of an organism receive signals from their environments and respond accordingly. Even the unicellular eukaryotes receive signals secreted by other cells and respond. In the case of yeast, mating takes place by signaling between the yeast cells. Communication by cell signaling in a multicellular organism has become a vast and important part of various fields of biology.

Question

In muscle cells, when adrenaline binds to beta-adrenergic receptor, it trigger signaling cascade leading to active glycogen phosphorylate breaks up glycogen into glucose subunits (Glycogen -> G1P). Base on following figure, describe this signaling cascade:

adrenaline
adenylyl
cyclase
CYTOSOL
GDP
ATP
dissociated
R-subunit
of PKA
CAMP
inactive PKA
active
РКА
phosphorylase
kinase
glycogen
phosphorylase
GLYCOGEN
G1P

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