
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Transcribed Image Text:coo
CH,-č-CoA + H,0
Acetyl-CoA CoA
CH,
но-с-соо
coo
CH,
Citrate čoo
Oxaloacetate
NADH
Çoo
CH,
сн-соо
сн-он
NAD
CH,
Malate
но-с-н
Coo
Isocitrate CoO
NAD
coo
NADH + H
CH
+ co,
Fumarate
HC
Coo
CH,
CH,
a-ketoglutarate
FADH,
NAD
• COA
NADH + H
• co,
FAD
Succinate
čoo
CH,
-CH,
Succinyl-CoA
CH,
coo
GTP + COA
GDP• P.
COA
In step 4 of this cycle the a-ketoglutarate complex uses the following cofactors or coenzymes
which are also used by
O A. Zn", Mg**; pyruvate carboxylase
В.
FAD; dihydrolipoyl transacetylase
TPP, COASH, Lipoic Acid; pyruvate carboxylase
OP. TPP, COASH, Lipoic Acid; pyruvate dehydrogenase complex
O E. biotin; pyruvate dehydrogenase complex
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