Answered: a. Draw out the pathways described…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Downstream actions of enzymes generate C22:4 Δ 7,10,13,16 and C22:5 Δ 7,10,13,16,19, which are converted to final products C22:5 Δ 4,7,10,13,16 and C22:6 Δ 4,7,10,13,16,19 . a. Draw out the pathways described above. Provide accurate line drawings for each lipid described b. For each step, identify if an elongase and/or desaturase is used. If a desaturase is used, indicate the type (for example  9 desaturase). c. For each step indicate whether the parasite could be using an enzyme from the human host to complete the step. Briefly justify your choices. d. This pathway is being considered as a parasite-specific target for drugs (to treat parasitic infections). Which step would you choose to target and why?

Definition Definition Organism that lives in the body of another organism and obtains food at the expense of the host. A parasite can directly or indirect harm the host. There are two kinds of parasites: internal and external. An internal parasite lives inside another organism and is known as an endoparasite. An external parasite lives on the body surface of the host and is known as an ectoparasite. Protozoa and helminths are examples of major human parasites.

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