A) The biotransformation of this drug: Choose all that apply. CH3 CH3 H,c-N. OH H,C OH он HO H,C. Phase I Phase II Reductive reaction Oxidative reaction Hydrolysis reaction glucuronic acid conjugation sulfate conjugation O methylation O acetylation product becomes less water soluble Porducts become more water soluble excretion of the products mostly happens in kidney excretion of the product mostly happens in feces B) What is the enzyme and coenzyme/cosubsrate ?

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter11: Reactions Of Alkyl Halides: Nucleophilic Substitutions And Eliminations
Section11.SE: Something Extra
Problem 79AP
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A) The biotransformation of this drug: Choose all that apply.
CH3
CH3
OH
H,C
он
он
HO
H,C.
Phase I
Phase II
Reductive reaction
Oxidative reaction
Hydrolysis reaction
glucuronic acid conjugation
sulfate conjugation
O methylation
O acetylation
product becomes less water soluble
Porducts become more water soluble
excretion of the products mostly happens in kidney
excretion of the product mostly happens in feces
B) What is the enzyme and
coenzyme/cosubsrate ?
Transcribed Image Text:A) The biotransformation of this drug: Choose all that apply. CH3 CH3 OH H,C он он HO H,C. Phase I Phase II Reductive reaction Oxidative reaction Hydrolysis reaction glucuronic acid conjugation sulfate conjugation O methylation O acetylation product becomes less water soluble Porducts become more water soluble excretion of the products mostly happens in kidney excretion of the product mostly happens in feces B) What is the enzyme and coenzyme/cosubsrate ?
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