A solution of the enzyme glycogen synthase incubated at 45°C lost 70% of its activity in 3 minutes„but when incubated at 45°C in the presence of a very large concentration of its substrate UDP-Glucose, it lost only 3% of its activity in the same amount of time, Why?CluCH,OHCH, OHHO,онCH;OHCH2OHноHOонHOUDPO-P-0OHOHNHo--oCH, OHCH2OHCH,OHOH OHHOUDP-glucose binding makes it easier for the enzyme to unfold.The enzyme likely had phosphate groups added through covalent modification.O Interactions with the bound UDP-glucose stabilize the tertiary structure of glycogen synthase.The UDP-Glucose is a positíve effector which increases the enzyme activity.

The enzyme loses its activity indicates that the tertiary structure (functional structure) of the…

A solution of the enzyme glycogen synthase incubated at 45°C lost 70% of its activity in 3 minutes but when incubated at 45°C in the presence of a very large concentration of its substrate UDP- Glucose, it lost only 3% of its activity in the same amount of time, Why? CH OH CH, OH CH,OH CH,OH HO HO, HO UDP O-0 OH OH NH 5,5,5 CH, OH CHOH CH,OH он он Он он HO UDP-glucose binding makes it easier for the enzyme to unfold. The enzyme likely had phosphate groups added through covalent modification. Interactions with the bound UDP-glucose stabilize the tertiary structure of glycogen synthase. The UDP-Glucose is a positive effector which increases the enzyme activity.

A solution of the enzyme glycogen synthase incubated at 45°C lost 70% of its activity in 3 minutes but when incubated at 45°C in the presence of a very large concentration of its substrate UDP- Glucose, it lost only 3% of its activity in the same amount of time, Why? CH OH CH, OH CH,OH CH,OH HO HO, HO UDP O-0 OH OH NH 5,5,5 CH, OH CHOH CH,OH он он Он он HO UDP-glucose binding makes it easier for the enzyme to unfold. The enzyme likely had phosphate groups added through covalent modification. Interactions with the bound UDP-glucose stabilize the tertiary structure of glycogen synthase. The UDP-Glucose is a positive effector which increases the enzyme activity.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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