Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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- Below are the general steps of protein synthesis. What is the correct sequence of protein synthesis? 1-ribosome bonds amino acids together; 2-mRNA leaves the nucleus; 3- tRNA molecules pick up amino acids; 4-DNA double helix unwinds; 5-tRNA anticodon links with mRNA codon; 6-polypeptide chain completed; 7-mRNA binds to ribosome; 8-mRNA transcibedarrow_forwardYou plan to synthesize a peptide to be used as a vaccine to treat melanoma, a particularly aggressive form of skin cancer. Normally, gp100, a protein on the surface of melanocytes, activates cell growth when it is bound by its ligand. Activation of the growth pathway depends on the presence of threonine in the ligand. The effective peptide vaccine will mimic the natural ligand, but won’t cause cell growth and division. Below is the sequence of the natural ligand: LDMKTAG In order to ensure your newly designed peptide vaccine does not cause cell growth upon binding, you must substitute the Threonine residue at position 5. What amino acid would you replace it with, bearing in mind that the peptide should still be similar enough to bind to the gp100 protein in the surface of melanocytes. Explain your choice. Your vaccine will be administered as a topical cream, and you require your peptide to have an overall neutral charge in order to be functional. At what pH should you formulate…arrow_forwardWhich of the following statements about the splicesome is correct? The spliceosome controls the translation process, ensuring that only exons are translated. O The spliceosome removes introns into mRNA sequences before translation. O The spliceosome inhibits transcription of noncoding DNA regions. The spliceosome contains both protein and a functional type of RNA known as SİRNAarrow_forward
- In protein synthesis, DNA transcription records the genetic message, while ribosomal ______________ interprets the message. ________________ carries the genetic code to the ribosomes to facilitate protein/amino acid synthesis. The genetic message to make a specific amino acid in a protein, is carried by a specific three nucleotide unit on the messenger RNA called a During transcription, the nitrogen base adenine on the DNA bonds with the nitrogen base ______________ on the messenger RNA. The enzyme __________________ unwinds the DNA double helix in DNA transcription.arrow_forwardIf the gene undergoing protein synthesis consists of 24 bases, how many codons does that result in? How many amino acids will the protein consist of?arrow_forwardShown below is a cartoon of a genetic oscillator. a) Convert into a Forrester diagram, state variables are D, m, E, S and P. As a reminder, dashed lines serve control/regulation. b) In a sentence, what causes the cyclic behavior in the formation of the product? DNA D mRNA Enzyme Substrate Product I 3arrow_forward
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