Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Consider the following DNA coding strand:
5' - ATGTACGGCGAATAA-3'
a) Determine the sense strand.
b) Demonstrate what the mature MRNA strand may look like. (Refer to the
underlined bases as exons.)
c) Determine the polypeptide chain (as well as the MRNA sequence).
Be sure to include 3' and 5' ends in your response where necessary.
MRNA Codon/Amino Acid Chart
First Base
Second Base
Third Base
A
G
UCU¬
UAU1
FTyrosine (Tyr)
UACJ
UUU1
Phenylalanine
UGU,
FCysteine (Cys)
UGC-
UUC-
(Phe)
UC
Serine (Ser)
UCA
UGA - Stop
UUA1
FLeucine (Leu)
UUGJ
UAAT
A
UCG-
Stop
UAGJ
UGG - Tryptophan (Trp)
G
CAU1
Histidine (His)
CAC
CUUT
CCU1
CGUT
U
CUC
FLeucine (Leu)
CUA
CGC
Proline (Pro)
CCA
FArginine (Arg)
CGA
CAA1 Glutamine
A
CAG (Glu)
CGG-
CUG-
CCGJ
G
AGUT
FSerine (Ser)
AGC-
AUUT
ACU1
AAUT
U
| Asparagine
AACJ (Asn)
AUC FIsoleucine (lle) ACC
Threonine
(Thr)
A
AUA-
ACA
AAA1
AGA7
A
Start Methionine
(Met)
FLysine (Lys)
AAG-
FArginine (Arg)
AGG-
AUG
ACG-
G
GUUT
GCU
GAU,
GGUT
U
Aspartic Acid
GACJ (Asp)
GUC
GCC
GGC
G
Fvaline (Val)
FAlanine (Ala)
Glycine (Gly)
GUA
GCA
GAAJ Glutamic Acid GGA
A
GAGJ (Glu)
GGG-
GUG-
GCG-
G
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Transcribed Image Text:Consider the following DNA coding strand: 5' - ATGTACGGCGAATAA-3' a) Determine the sense strand. b) Demonstrate what the mature MRNA strand may look like. (Refer to the underlined bases as exons.) c) Determine the polypeptide chain (as well as the MRNA sequence). Be sure to include 3' and 5' ends in your response where necessary. MRNA Codon/Amino Acid Chart First Base Second Base Third Base A G UCU¬ UAU1 FTyrosine (Tyr) UACJ UUU1 Phenylalanine UGU, FCysteine (Cys) UGC- UUC- (Phe) UC Serine (Ser) UCA UGA - Stop UUA1 FLeucine (Leu) UUGJ UAAT A UCG- Stop UAGJ UGG - Tryptophan (Trp) G CAU1 Histidine (His) CAC CUUT CCU1 CGUT U CUC FLeucine (Leu) CUA CGC Proline (Pro) CCA FArginine (Arg) CGA CAA1 Glutamine A CAG (Glu) CGG- CUG- CCGJ G AGUT FSerine (Ser) AGC- AUUT ACU1 AAUT U | Asparagine AACJ (Asn) AUC FIsoleucine (lle) ACC Threonine (Thr) A AUA- ACA AAA1 AGA7 A Start Methionine (Met) FLysine (Lys) AAG- FArginine (Arg) AGG- AUG ACG- G GUUT GCU GAU, GGUT U Aspartic Acid GACJ (Asp) GUC GCC GGC G Fvaline (Val) FAlanine (Ala) Glycine (Gly) GUA GCA GAAJ Glutamic Acid GGA A GAGJ (Glu) GGG- GUG- GCG- G
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